Ganglioneuromas (GNs) are benign, slow growing and well differentiated neuroectodermal neoplasias. They are derived from developing neuronal cells of the sympathetic nervous system. They occur mostly in children and are located in the posterior mediastinum, retroperitoneum. We present a case of incidental solitary polypoid ganglioneuroma of the colon. A 70 year old woman underwent colonoscopy for colon cancer screening. She has no abdominal or intestinal symptoms. In hepatic flexure of the colon a spherical polypoid lesion that was 1.4 cm in diameter was detected endoscopically. Biopsy was taken from the polyp. The histopathology revealed a biphasic polypoid tumor with ganglion cells and schwannian stroma on hematoxylin and eosin stain. Final histopathological diagnosis was polypoid ganglioneuroma of the colon. Ganglioneuromatous polyposis and diffuse ganglioneuromatosis are associated with several systemic syndromes. Solitary GNs are generally asymptomatic. Treatment of GNs depends on their size, location, and clinical findings such as bleeding or obstruction. Prognosis is usually excellent. Polypectomy is curative for polypoid GN. However the patients with ganglioneuromatous polyposis and diffuse form may need colectomy.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
customersupport@researchsolutions.com
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.