A 68-year-old white man presented to the dermatology clinic with a 2-year history of a recurrent wart on the right oral commissure and two brown lesions on each corner of his lower lip. The patient had previously been treated for warts of the right oral commissure and for bilateral angular cheilitis. His past medical history was significant for excision of erythroplasia of Queyrat on the penis in 1977 that had been present for 20 years. The patient had worked on the family farm as a teenager and had daily exposure to arsenical insecticides.
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