When aziridines (1) were treated with acetyl compounds, such as acetyl chloride, acetic acid, acetic anhydride, and thioacetic acid, the corresponding acetamide derivatives were obtained in good yields. In the case of acetyl chloride, some derivatives of N-(2-chloroethyl)acetamide (5) were found to be unstable in the face of moisture; they were easily hydrolyzed to give N-(2-hydroxyethyl) acetamide hydrochlorides (3). The NMR spectrum of N-(2-mercaptoethyl)-N-benzylacetamide (12) was discussed.
Die Aziridine (I) reagieren mit den Acetyl‐Verbindungen (II) zu den Acetamid‐Derivaten (III) (Ausbeute 58‐99%), die im Fall von R4 = Cl zum Teil in Gegenwart von Feuchtigkeit instabil sind und zu den Hydroxyäthylaminhydrochloriden (IV) (66‐95%) hydrolysiert werden.
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