In a prospective, randomized, masked study the effect of sodium hyaluronate (Healon) and timolol on the acute intraocular pressure rise after extracapsular cataract extraction with implantation of a posterior chamber lens were evaluated. Intraocular pressure was measured preoperatively and 3-6 h and 24 h postoperatively. When no timolol was used, a significant rise in intraocular pressure was observed at 3-6 h, whether or not Healon was aspirated. Timolol reduced the intraocular pressure rise, especially during the first 3-6 h after surgery. When timolol was not applied at the end of surgery, IOP exceeded 30 mmHg in 28% 3-6 h postoperatively, compared to only 4% when timolol was applied.
One-piece, open-loop flexible anterior chamber lens, Symflex 350B, was implanted in 90 eyes, 26 after extracapsular cataract extraction (ECCE), and 57 after intracapsular cataract extraction (ICCE), and in 7 cases the operation was done as a secondary implantation. The cohort was followed 3.4-4.4 years, 68 eyes were included in the last examination. At the final examination 7 eyes (10.29%) had developed corneal oedema. 6 eyes had undergone ICCE and one eye had been secondarily implanted. In no case was vaulting or malposition of the intraocular lens (IOL) found. The decompensation appeared shortly after the operation in 2 cases, one case being a secondary implantation between 1 year and 3-4 years after implantation. All extracapsularly operated eyes showed normal corneas, but the difference was not statistically significant. Neither ovalling of the pupils, nor tissue growth over the haptic feet in the anterior chamber angle, nor the visual acuity (VA) changed significantly from the 1-year to the 3-4-years examination. The intraocular pressure (IOP), however, was statistically significantly lowered 3-4 years postoperatively.
90 anterior chamber lenses, ccSymfkex 350 Bn, were implanted in a prospective study. This preliminary report shows favourable visual results and relatively non-serious complications in rather low frequency. Gonioscopy shows that the haptic of the lens is uniformly and exactly positioned in the chamber angle.
The 12 h IOP control achieved by a single application of a newly developed ophthalmic solution containing 0.5% timolol and 2% resp. 4% pilocarpine was compared with that obtained by 1 dose of timolol 0.5% alone in 33 patients with manifest open angle glaucoma or ocular hypertension. The combined solutions gave a significantly better 12 h IOP control, evidenced by both a reduced mean diurnal IOP and a decreased frequency of larger pressure peaks.
In a prospective, randomized and masked study the quantitative effect of sodium hyaluronate (Healon) on early postoperative intraocular pressure after cataract surgery was evaluated. At the end of planned extracapsular cataract extraction with implantation of posterior chamber lens, 0.1 ml or 0.2 ml of Healon was injected into the anterior chamber. The intraocular pressure was measured preoperatively, 3-6 h and 24 h postoperatively. All patients received topical timolol at the end of surgery. The results were compared to eyes operated with identical techniques where Healon was aspirated at the end of surgery. Three to six hours postoperatively a significant drop in mean intraocular pressure from preoperative pressure occurred when Healon was aspirated, but no statistical differences in mean intraocular pressure appeared when 0.1 ml or 0.2 ml of Healon was injected. The frequencies of pressure rise above 30 mmHg show no differences among the groups. Twenty-four hours postoperatively a significant pressure elevation from mean preoperative pressure occurred when 0.1 ml or 0.2 ml Healon was injected compared to the group were Healon was aspirated at the end of surgery. Similar results are seen when pressure rise above 30 mmHg are concerned.
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