This article describes osteomyelitis of the sphenoid skull bone in a maltanese dog due to Cryptococcus neoformans var. neoformans infection. The affected dog was subjected to physical and neurological examinations. Complete blood count (CBC), biochemistry profile, lymph node biopsy, cerebrospinal fluid (CSF) examination were also performed. This case report describes abnormalities in magnetic resonance imaging (MRI) examination as well as the histhopathologic lesions of the skull bones and neurological symptoms of the dog.
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