Among 614 men who have sex with men in San Diego County with early syphilis during January 2004 to June 2007, 74 (11.7%; 95% confidence interval: 9.3%-14.4%) had repeat syphilis within 2 years. HIV-infected MSM were more likely to have repeat syphilis (odds ratio: 1.9; 95% confidence interval: 1.1, 3.4).
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