Morphine is the opioid most commonly used for neonatal pain management. In intravenous form, it is administered as continuous infusions and intermittent injections, mostly based on empirically
We present deformable mirrors for the intra-cavity use in high-power thin-disk laser resonators. The refractive power of these mirrors is continuously adaptable from -0.7 m-1 to 0.3 m-1, corresponding to radii of curvature ranging between 2.86 m (convex) and 6.67 m (concave). The optimized shape of the mirror membrane enables a very low peak-to-valley deviation from a paraboloid deformation over a large area. With the optical performance of our mirrors being equal to that of standard HR mirrors, we were able to demonstrate the tuning of the beam quality of a thin-disk laser in a range of M2 = 3 to M2 = 1 during laser operation at output powers as high as 1.1 kW.
Wavefront distortions caused by the convection of heated ambient air in front of the laser crystal induce severe pump-power-dependent misalignment in thin-disk laser (TDL) resonators. This effect is particularly pronounced in fundamental mode operation and limits the output power when no realignment of the resonator is possible during operation. In this Letter, we present a new approach to passively compensate for this misalignment instability by exploiting the spectral dispersion of a highly efficient grating-waveguide mirror used as a cavity end-mirror in a Littrow configuration. By this, it was possible to almost triple the output power of a fundamental mode Yb:LuAG TDL pumped at 969 nm.
We report on the first demonstration of a radially polarized passively mode-locked thin-disk oscillator. Radial polarization was achieved by the use of a novel circular grating waveguide output coupler. We showed mode-locked operation up to a maximum average output power of 13.3 W with an optical efficiency of 21.8%. The degree of radial polarization of the emitted beam was measured to be 97±1%. The laser system generated pulses with a duration of 907 fs and an energy of 316 nJ corresponding to a peak power of 0.35 MW. To the best of our knowledge, these values exceed the performance of previously reported radially polarized mode-locked oscillator systems.
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