This paper reports large light-induced reversible and elastic responses of graphene nanoplatelet (GNP) polymer composites. Homogeneous mixtures of GNP/polydimethylsiloxane (PDMS) composites (0.1-5 wt%) were prepared and their infrared (IR) mechanical responses studied with increasing pre-strains. Using IR illumination, a photomechanically induced change in stress of four orders of magnitude as compared to pristine PDMS polymer was measured. The actuation responses of the graphene polymer composites depended on the applied pre-strains. At low levels of pre-strain (3-9%) the actuators showed reversible expansion while at high levels (15-40%) the actuators exhibited reversible contraction. The GNP/PDMS composites exhibited higher actuation stresses compared to other forms of nanostructured carbon/PDMS composites, including carbon nanotubes (CNTs), for the same fabrication method. An extraordinary optical-to-mechanical energy conversion factor (η(M)) of 7-9 MPa W(-1) for GNP-based polymer composite actuators is reported.
Circulating tumor cells (CTC) are cells that have detached from primary tumors and circulate in the bloodstream where they are carried to other organs, leading to seeding of new tumors and metastases. CTC have been known to exist in the bloodstream for more than a century. With recent progress in the area of micro- and nanotechnology, it has been possible to adopt new approaches in CTC research. Microscale and nanoscale studies can throw some light on the time course of CTC appearance in blood and CTC overexpression profiles for cancer-related markers and galvanize the development of drugs to block metastases. CTC counts could serve as endpoint biomarkers and as prognostic markers for patients with a metastatic disease. This paper reviews some of the recent researches on using micro- and nanotechnology to capture and profile CTC.
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