No abstract

No abstract

Purpose: This work aimed to analyze the 100 most-cited articles on antivascular endothelial growth factor (anti-VEGF) inhibitors. Methods: A literature search for anti-VEGF inhibitors using the Web of Science was completed using the bibliographic databases for peer-reviewed literature published in Ophthalmology, the New England Journal of Medicine, Journal of the American Medical Association, and Lancet. Primary outcomes were the most frequently cited articles and journals with the most citations as well as the specific drug and disease process studied. Results: There were 42 696 cumulative citations among the top 100 articles. The articles were published between 2004 to 2016, with most articles published in 2006. Ophthalmology published the greatest number of articles among the top 100 at 48, whereas the New England Journal of Medicine has the most citations per publication at 1714. Ranibizumab was the medication researched in most articles at 56, followed by bevacizumab at 48, aflibercept at 10, and pegaptanib at 9. Forty-two articles investigated treatment of age-related macular degeneration, followed by 24 investigating diabetic macular edema, 10 for retinal vein occlusion, 8 for proliferative diabetic retinopathy, 2 for retinopathy of prematurity and polypoidal choroidal vasculopathy, and 1 for corneal neovascularization. Conclusions: As evidenced by the considerable number of citations accumulated over the past 20 years, anti-VEGF inhibitors have led to significant research in ophthalmology.

No abstract

Objective: To evaluate SCImago’s top ranked ophthalmology journals, comparing them with the top medical and surgical journals. Methods: Data over 20 years was extracted for the top-ranked 20 ophthalmology, top 5 medical, and top 5 surgical journals based on SCImago Journal Ranking (SJR). Trends in SJR, self-citations, external citations per document, uncited documents, international collaboration, citations per document, and total citations were identified. ANCOVA analysis was utilized to further characterize average trends over time between medicine, ophthalmology and surgery. Results and Discussion: The fields of medicine, ophthalmology, then surgery had the highest SJR while medicine, surgery, then ophthalmology had the highest h-indices. Medicine had 1.01 uncited per cited article, compared to 0.54 and 0.43 for ophthalmology and surgery. Percent of self-citation was 5.9% for ophthalmology, 5.0% for surgery, and 0.56% for medicine; however, self-citations per article were the highest for surgery. International collaboration was highest for ophthalmology (19.14%) compared to surgery (16.75%) and medicine (8.00%). Medicine increased disproportionately in SJR (p= 0.0037), citations per document (p <0.001), and total citations (p<0.001) compared to surgery and ophthalmology over the last 20 years. Ophthalmology had the largest decrease in the percent of uncited articles (p=0.0006). Conclusion: Ophthalmology has a lower h-index compared to surgery and medicine but was comparable when using more qualitative measures including SJR and uncited articles. Ophthalmology has the highest number of self-citations and the greatest level of international collaboration.