Introduction: Evidence suggests that in convenience stores across the United States (U.S), sales of e-cigarettes (EC) continue to grow, indicating their rising popularity. ECs have been touted as a means for traditional cigarette (TC) smokers to quit smoking. However, the dramatic increase in the number of adolescents and young adults using e-cigarettes (vaping) in America is a cause for concern as their long-term effects remain unknown. Methods: Search was done by accessing PubMed/Medline, EBSCO, and PsycINFO databases. The search string used was "(Cigarettes OR E-Cigarettes* OR Vaping) AND (Oxidative Stress* OR Reactive Oxygen Species (ROS)) AND (Adolescents OR Teens OR Young Adults)". The electronic databases were searched for titles or abstracts containing these terms in all published articles between January 1, 1970, and June 30, 2019. Over 3000 articles were found in the first round of search which was filtered to 129 articles. Results: Oxidative Stress is a critical underlying molecular factor that drives the harmful effects of traditional cigarettes. The developing brain is particularly vulnerable to the harmful effects of oxidative stress and e-cigarettes just like traditional cigarettes induces oxidative stress. Many ecigarette components including the flavoring, vapor, e-liquids and metallic coil, trigger oxidative stress, indicating that both nicotine and non-nicotine e-cigarette use may be harmful.Conclusions: E-cigarettes use could potentially play a role in adolescent/young adults social maladjustments including poor learning and academic performance, increased aggressive and impulsive behavior, poor sleep quality, attention deficits, impaired memory, and cognition, and increased depression and suicidal ideation. The government, parents, school authorities and clinicians should be advised on these potentially harmful effects.

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Cancer is the second leading cause of noncommunicable disease deaths in the world. In 2018, there were over 18 million new cancer cases and approximately 10 million people died from the disease globally. In 2019, almost two million new cases of cancer will be diagnosed in USA and over 600,000 people are expected to die from the disease. The incidence of cancer is expected to rise because of lifestyle changes and a rapidly aging population. Evidence suggests that early detection is critical to reducing cancer morbidity and mortality. In this paper, the development of an integrated smart wearable and biomarker detection system is proposed to help reduce cancer morbidity and mortality. The potential benefits and limitations of the system are discussed.

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Scholars across an array of disciplines including social psychologists have been trying to explain the meaning of love for over a century but its polysemous nature has made it difficult to fully understand. In this paper, a quadruple framework of attraction, resonance or connection, trust, and respect are proposed to explain the meaning of love. The framework is used to explain how love grows and dies and to describe brand love, romantic love, and parental love. The synergistic relationship between the factors and how their variations modulate the intensity or levels of love are discussed.