We report a particular case of fixed drug eruption (FDE), in its erythematous and pigmented form, as a fixed pigmented erythema (FPE), which manifests in a generalized form, evolving for three years, and discuss the imputability to piroxicam and the Ramipril/Hydrochlorothiazide combination. Indeed, chronological, semiological, bibliographic criteria, were imprecise and non-discriminatory. We ended up retaining the diagnosis of fixed pigmented erythema (FPE) of particular diffuse presentation induced probably by piroxicam, based on clinical, histological and evolutive criteria. However, it remains a mixed zone between drug-induced hyperpigmentation and generalized fixed pigmented erythema with diffuse hypermelanosis.
Goals1. Establish demographic and topographic mapping of hyperpigmentation's associated with antitumor chemotherapy.2. Through the evaluation of MELASQOL, we have shown that these hyperpigmentation's associated with a high Me-lasQol score can be improved by dermatological intervention to ensure a better quality of life for cancer patients.
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