Objective This study aimed to explore the prevalence of hyperuricemia among the general adult population in Shenzhen and to determine the risk factors of hyperuricemia. Methods A total of 9337 cases who underwent physical examination in The Seventh Affiliated Hospital of Sun Yat-Sen University in 2020 were enrolled in this study. The binary logistic regression analysis was performed to determine potential risk factors of hyperuricemia. Result The overall prevalence rate of hyperuricemia in the studied population was 40.5% (3783/9337). Subgroup analysis showed that the prevalence of males was 52.8% (3046/5769) and the prevalence of females was 20.7% (737/3568). Moreover, among different age groups (≤29 years old, 30-39 years old, 40-49 years old, 50-59 years old, and ≥60 years old), the prevalence rate of males was significantly higher than that of females (P<0.05). To further determine the relationship between the body mass index (BMI) and hyperuricemia, the population with normal BMI was set as the control group. After controlling for gender and age, the prevalence rate of hyperuricemia in the overweight population increased by 1.799 times; and the prevalence rate in the obese and very obese population increased by 3.283 times and 3.830 times, respectively. Conclusion The data presented in this study demonstrated that the prevalence rate of hyperuricemia is high in Shenzhen, espeially in males. Moreover, the level of BMI is significantly linked to the prevalence of hyperuricemia. Therefore, early interventions should be carried out to address the high prevalence of hyperuricemia in male and obese populations.
[Objective] Polycystic ovary syndrome (PCOS), a common female health condition caused by a hormonal imbalance due to the ovaries producing excess male hormones, is also considered a chronic endocrine-metabolic syndrome. According to the traditional Chinese medicine (TCM) theory, multiple factors including insufficiency of kidney and liver as well as phlegm dampness may result in PCOS. This study aimed to investigate the distribution pattern of TCM syndrome types in patients with PCOS, and to determine the glucose metabolism status among these patients. [Methods] A total of 60 patients diagnosed with PCOS in our center were enrolled in this study. These patients were classified into three groups based on their TCM syndrome types, including phlegm dampness syndrome, liver stagnation syndrome, and kidney insufficiency syndrome. A uniformly formulated basic information sheet was collected, and all of them underwent glucose tolerance test (OGTT). The correlations of body mass index (BMI), waist to hip ratio (WHR), and glucose metabolism in patients with different syndromes were compared. [Results] The patients with phlegm dampness syndrome type (n=32) were the most among these 60 patients with PCOS, accounting for 53.33%, followed by liver stagnation syndrome (n=18; 30%) and kidney insufficiency syndrome (n=10; 16.67%). The BMI and WHR of patients with phlegm dampness syndrome were higher than those with liver stagnation syndrome and kidney insufficiency syndrome (P<0.01). There was no significant difference in the incidence of abnormal glucose metabolism (IFG/IGT/diabetes) among the three groups (P>0.05). [Conclusions] The main TCM syndrome type in patients with PCOS is phlegm dampness syndrome, which was linked to obesity and abdominal obesity.
Oblique vaginal septum syndrome (OVSS) is a rare congenital disorder characterized by uterus didelphys, hemivaginal septum, and unilateral renal agenesis. Its clinical characteristics vary among different patients. Herein we report a case of OVSS with difficulty in defecation as the initial symptom and diagnosed with ultrasound and laparoscopic exploration. This 13-year-old girl was admitted to our hospital with the complaint of difficulty in defecation for more than 1 month and difficulty in urination for 6 days. Her ultrasound test showed that the left kidney was not displayed, and the right kidney was compensatory enlargement. A giant cystic-solid mass (110 mm × 96 mm × 87 mm) was seen in the pelvic cavity. Under laparoscopy, a huge mass was seen in the abdominal cavity. The surface resembled the seromuscular layer of the uterus. A uterine organ was seen on both sides of the tumor, and both fallopian tubes and ovaries were connected. The size of the right uterus was about 3 cm × 2 cm. The right fallopian tube and ovary were normal in appearance. The left uterus was enlarged (about 6 cm x 5 cm). The left fallopian tube was enlarged and contained a large amount of brown blood stains, and blood stains were seen flowing out from the umbrella end. The hysteroscopic incision and repair surgery were then performed. Most patients with OVSS presented with dysmenorrhea, abdominal pain, pelvic mass, and foul mucopurulent discharge, while in this case, difficulty in defecation was the initial symptom. Thus, this case report provided evidence supporting the heterogeneity of this disorder.
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