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Drug safety management is an important issue in China drug management system and attracts great attentions from the whole society. In order to reduce drug incident, this study discusses some important elements associated with China drug safety management system and analyzes the data collected by questionnaires. Besides, a methodology for rating the important elements is described and applied. The non-structural fuzzy group decision method not only considers the insufficient precise information but also combines the opinions of different kinds of respondents in China's four municipalities. The results indicate that the sample systems are the most important in these important elements, and the order of importance is sampling systems, licensing systems, traceability systems, transaction models, pharmacovigilance and emergence management. This study not only points out the important ranking of the pivotal elements in China drug safety management but also gives some specific proposals about how to enhance drug safety management in China.