This study was supported by the Université Catholique de Bruxelles. Emanuel N. van den Broeke is supported by the Fonds de Recherche Clinique UCL.

Synopsis Central sensitization is (1) increasingly interpreted as central nervous system hyperexcitability that accounts for a general increase in sensitivity, and (2) used to explain a variety of pain and nonpain symptoms. In this commentary, we argue that such a broad interpretation might not be clinically useful because it fails to distinguish one patient from another based on pathophysiological mechanisms and does not facilitate tailored treatment. We recommend that clinicians use a person-centered approach when assessing and managing patients, considering the different interacting processes/mechanisms that can contribute to a patient's clinical presentation. J Orthop Sports Phys Ther 2021;51(5):204–206. Epub 15 Mar 2021. doi:10.2519/jospt.2021.10340

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High-frequency stimulation of the skin induces secondary pinprick hyperalgesia but does not affect pressure pain thresholds either locally or at more distant body sites.

Temporomandibular disorders (TMD) are a collective term encompassing conditions affecting the masticatory system resulting in pain and disability. 1 The prevalence of TMD-related pain is about 10 per cent in the adult population. 2 Pain in the pre-auricular areas and/or localised in the masticatory muscles, joint sounds and deviation or restriction of jaw movement are the most common