Jak kinases are critical signaling components in hematopoiesis. While a large number of studies have been conducted on the roles of Jak kinases in the hematopoietic cells, much less is known about the requirements for these tyrosine kinases in other tissues. We have used loss of function mutations in the Drosophila Jak kinase Hopscotch (Hop) to determine the role of Hop in eye development. We find that Hop is required for cell proliferation/survival in the eye imaginal disc, for the differentiation of photoreceptor cells, and for the establishment of the equator and of ommatidial polarity. These results indicate that hop activity is required for multiple developmental processes in the eye, both cell-autonomously and nonautonomously.
This paper takes a new look at the methods of embodiment for psychotherapy supervision. It makes a rigorous distinction between knowledge derived via language and knowledge derived via the body without the intervention of conscious thought and above all language.In an account of a study whereby the principal researcher and her co researchers, all professional practitioners of dance movement psychotherapy, the genesis and development of new tools designed to capture the connection between movement and the possibility of "languaging" the embodied experience (Sheets-Johnstone, 2007, p. 1) is shown. An unexpected outcome resulted in which the methodology developed for the study proved to be useful for clinical supervision. Of the several different models developed, one, a model for self-supervision, is presented here as a practical example of how to access the knowledge of the body. In putting forward implications for practice, the authors suggest that the integration of movement and writing may be beneficial not only for clinical supervision in dance movement psychotherapy, but also for body psychotherapies, arts therapies, and for any verbal approaches of psychotherapy supervision that aim to integrate and explore the embodied experience.
This paper describes how medical cover was provided for a large music festival attended by 70,000 people. The organisational structure of the team and the workload encountered are related. As well as illustrating the value of on-site medical cover in minimising the workload for local health services, some specific hazards of such events are discussed.
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