Abstract. In order to blend the liquid in the microfluidic chip adequately, this paper presented a novel mixing scheme in which the species streams was mixed via the application of Lorenz chaotic system algorithm to three pair of parallel electrodes mounted on the surfaces of the mixing chamber to produces chaotic electric fields. To select the better microelectrode arrays, the paper also discussed the advantages of the indium tin oxide (ITO) materials and used ITO to design the microelectrode array. Finally, simulations of the mixing process under the control of the proposed chaotic electric fields are performed. Analysis result shows that the correlation coefficient between the largest Lyapunov exponents on Lorenz chaotic system and chaotic flow behavior is 0.72 which shows a better synchronism, and it also proved that ITO is a better material to fabricate the microelectrode arrays.
Pathological cardiac remodeling is an important cause of sudden cardiac death and other cardiovascular diseases in athletes. Unfortunately, people involved in long-term intense endurance exercise (especially professional athletes) do not fully understand the cause and health risks of
pathological cardiac remodeling, resulting in pathological cardiac remodeling developing into irreversible damage, which seriously affects sports careers and the postretirement life of athletes. Studies have shown that myocardial inflammation caused by long-term and repeated high-intensity
exercise is a prerequisite for inducing pathological remodeling and that effective inhibition of inflammation can block or reverse the pathological process of pathological remodeling. This preliminary study showed that moxibustion at CV 8 inhibited the p38 mitogen-activated protein kinases/nuclear
factor-κβ (p38 MAPK/NF-κβ) signaling pathway in myocardium, reduced the expression of cyclooxygenase-2 (COX-2), interleukin-6 (IL-6), and tumor necrosis factor(TNF-α), significantly improved myocardial morphology and function in rats under going long-term and repeated
high-intensity exercise, and effectively prevented pathological cardiac remodeling. Moxibustion at CV 8 provides a new physical therapy and experimental basis for the treatment of pathological cardiac remodeling in clinical practice.
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