Recently, with the continuous development of human society and the continuous innovation of technologies, the intelligence era has arrived.Various intelligent electronic devices continue to be developed, in which flexible wearable electronic devices are highly favored by people. To meet the SmartMat.

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BackgroundFAM98A, a novel protein, is expressed in ovarian and colorectal cancer tissues. However, the association between FAM98A expression and the clinicopathological characteristics of non-small cell lung cancer (NSCLC) remains undetermined.Materials and methodsThe FAM98A expression pattern was determined in NSCLC samples and corresponding adjacent normal lung tissues using immunohistochemical staining and Western blotting. The association of FAM98A expression with clinicopathological characteristics was measured in 131 NSCLC samples. Finally, the overexpression and inhibition of FAM98A was performed in the A549 and SPC-A1 cell lines to explore its role in the development of lung cancer.ResultsWestern blot analysis of 20 paired NSCLC samples showed that expression of FAM98A was higher in lung cancer tissues than in the corresponding adjacent normal lung tissues (p<0.05). Immunohistochemical staining of 128 NSCLC specimens showed that expression of FAM98A was significantly higher in lung cancer samples than in adjacent normal lung tissues (118/128 vs 10/128; p<0.001). Positive expression of FAM98A was significantly related to tumor TNM stage (p<0.05) and lymph node metastasis (p<0.001). Additionally, overexpression of FAM98A induced an increase in the expression of phosphorylated P38, phosphorylated ATF2, and cyclin D1, which promoted proliferation of lung cancer cells. Correspondingly, the effects of FAM98A overexpression were reversed by administration of a specific inhibitor of phosphorylated P38.ConclusionFAM98A was overexpressed in the cytoplasm of NSCLC samples and correlated with advanced TNM staging and lymph node metastasis. Thus, FAM98A increases the expression of cyclin D1 by activating the P38-ATF2 signaling pathway and subsequently enhancing tumor cell proliferation; these results are promising and need further validation.

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In recent years, paper‐based functional materials have received extensive attention in the field of energy storage due to their advantages of rich and adjustable porous network structure and good flexibility. As an important energy storage device, paper‐based supercapacitors have important application prospects in many fields and have also received extensive attention from researchers in recent years. At present, researchers have modified and regulated paper‐based materials by different means such as structural design and material composition to enhance their electrochemical storage capacity. The development of paper‐based supercapacitors provides an important direction for the development of green and sustainable energy. Therefore, it is of great significance to summarize the relevant work of paper‐based supercapacitors for their rapid development and application. In this review, the recent research progress of paper‐based supercapacitors based on cellulose was summarized in terms of various cellulose‐based composites, preparation skills, and electrochemical performance. Finally, some opinions on the problems in the development of this field and the future development trend were proposed. It is hoped that this review can provide valuable references and ideas for the rapid development of paper‐based energy storage devices.

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With the continuous improvement of living standards and advancements in science and technology, composite materials with multiple functionalities are gaining high practical value in modern society. In this paper, we present a multifunctional conductive paper-based composite with electromagnetic (EMI) shielding, sensing, Joule heating, and antimicrobial properties. The composite is prepared by growing metallic silver nanoparticles inside the cellulose paper (CP) modified with polydopamine (PDA). The resulting CP@PDA@Ag (CPPA) composite has high conductivity and EMI shielding properties. Furthermore, CPPA composites demonstrate exceptional sensing, Joule heating, and antimicrobial properties. In addition, Vitrimer, a polymer with excellent cross-linked network structure, is introduced into CPPA composites to obtain CPPA-V intelligent electromagnetic shielding materials with shape memory function. These excellent properties show that the prepared multifunctional intelligent composite has exceptional EMI shielding, sensing, Joule heating, and antibacterial and shape memory properties. In short, this multifunctional intelligent composite material has great application prospects in flexible wearable electronics.