Mental illness is highly prevalent nowadays, constituting a major cause of distress in people’s life with impact on society’s health and well-being. Mental illness is a complex multi-factorial disease associated with individual risk factors and a variety of socioeconomic, clinical associations. In order to capture these complex associations expressed in a wide variety of textual data, including social media posts, interviews, and clinical notes, natural language processing (NLP) methods demonstrate promising improvements to empower proactive mental healthcare and assist early diagnosis. We provide a narrative review of mental illness detection using NLP in the past decade, to understand methods, trends, challenges and future directions. A total of 399 studies from 10,467 records were included. The review reveals that there is an upward trend in mental illness detection NLP research. Deep learning methods receive more attention and perform better than traditional machine learning methods. We also provide some recommendations for future studies, including the development of novel detection methods, deep learning paradigms and interpretable models.
Drug–drug interactions (DDIs) are crucial for drug research and pharmacovigilance. These interactions may cause adverse drug effects that threaten public health and patient safety. Therefore, the DDIs extraction from biomedical literature has been widely studied and emphasized in modern biomedical research. The previous rules-based and machine learning approaches rely on tedious feature engineering, which is labourious, time-consuming and unsatisfactory. With the development of deep learning technologies, this problem is alleviated by learning feature representations automatically. Here, we review the recent deep learning methods that have been applied to the extraction of DDIs from biomedical literature. We describe each method briefly and compare its performance in the DDI corpus systematically. Next, we summarize the advantages and disadvantages of these deep learning models for this task. Furthermore, we discuss some challenges and future perspectives of DDI extraction via deep learning methods. This review aims to serve as a useful guide for interested researchers to further advance bioinformatics algorithms for DDIs extraction from the literature.
Suicide is one of the leading causes of death worldwide. At the same time, the widespread use of social media has led to an increase in people posting their suicide notes online. Therefore, designing a learning model that can aid the detection of suicide notes online is of great importance. However, current methods cannot capture both local and global semantic features. In this paper, we propose a transformer-based model named TransformerRNN, which can effectively extract contextual and long-term dependency information by using a transformer encoder and a Bi-directional Long Short-Term Memory (BiLSTM) structure. We evaluate our model with baseline approaches on a dataset collected from online sources (including 659 suicide notes, 431 last statements, and 2000 neutral posts). Our proposed TransformerRNN achieves 95.0%, 94.9% and 94.9% performance in P, R and F1-score metrics respectively and therefore outperforms comparable machine learning and state-of-the-art deep learning models. The proposed model is effective for classifying suicide notes, which in turn, may help to develop suicide prevention technologies for social media.
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