Cutaneous squamous cell carcinoma is a malignant tumour of the keratinising cells of epidermis or its appendages. It constitutes of 20% of skin malignancy. UV radiation exposure is the most common cause of skin cancer with sun exposed skin of the face and upper trunk being the common site for occurrence. Long term exposure to chemical carcinogen, burn scar, chronic ulcer is among the other risk factors. Skin biopsy is the mainstay of diagnosis in a suspected lesion of SCC. Most SCC can be treated with local excision with margin of 5 mm and a margin of around 10 mm in high risk lesion. Other treatment modalities which do not define the margin status such as radiation therapy, cryosurgery, photodynamic therapy, electro dissection, topical agents like imiquimod can be used in small superficial lesions. The following is a case of 32-year-old male patient with atypical presentation of bilateral lower limb squamous cell carcinoma.
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