Early results from this real world, global experience are promising and indicate that endovascular AAA repair with the Endurant Stent Graft is safe and effective across different geographies and standards of practice. Longer-term follow-up is necessary to assess durability of these results.
We observed a clear trend toward improved outcomes after EV repair of thoracic aortic injuries compared with standard open repair. EV repair is emerging as the preferred method of repairing blunt thoracic aortic injuries in trauma patients with multiple injuries.
This study demonstrated a nonsignificant lower rate of groin SSI in high-risk revascularization patients with NPWT compared with standard dressing. Owing to a lower than expected infection rate, the study was underpowered to detect a difference at the prespecified level. The NPWT group did show significantly shorter mean hospital duration of stay compared with the standard dressing group.
The Importance of dissolved versus sediment-bound cadmium as uptake routes for the deposit-feeding polychaete Capitella species I and the toxicity and toxicokinetlcs of cadmium from these exposure routes were investigated. Effects were reported as changes in worm growth rate, egestion rate and allometry. Radioactive cadmium (""'Cd) was used as a tracer to examine the uptake (5 d) and subsequent depuration (6 d) of cadmium. Both effects and kinetics were investigated in systems with and without sediment. Individual Capitella sp. 1 were exposed to (1) dissolved (i.e. <0.45 pm) cadmium (water-only treatment), (2) sediment-bound cadmium (sediment-bound only treatment), or (3) both dissolved and sedment-bound cadmium (porewater & sediment treatment). The porewater concentration of dissolved cadmium in porewater & sediment treatments was set approximately equal to the dissolved concentration in water-only treatments (0, 25,50 pg Cd I-'). Worms in water-only treatments showed negative growth rates, w h~c h decreased linearly from -5 to -10% d-' with increasing cadmium concentration. Cadmium had no detectable effect on egestion rate or growth in the presence of sediment in elther sediment-bound only (ca 369: d.') or porewater & sedlnlent (ca 30% d-') treatments. Cadmium exposure had no detectable effect on the allometric exponent (I e area-length relation) in any of the treatments; however, worms in water-only treatments were relatively thinner than in the 2 treatments with sediment. Worms in porewater & sediment treatments took up ca 50-fold more cadmium (ca 195 ng Cd worm-') than worms In water-only treatments (3.9 ng Cd worm-') during 5 d of exposure. Sediment-bound cadmium was calculated to contribute 95 ?h of the total amount taken up by feeding worms. Starving worms retained all of the cadmium during the subsequent depuration period (6 d), and exhibited an increased weight-specific body burden (pg Cd g-' dry wt worm) due to shrinkage. In feeding worms, the decrease in weight-specific body burden was faster (T% = 3 d ) than the decrease in total body burden (pg Cd worm-'; 3/, = 11 d), indicating that both active excretion and dilution of cadmium body burden as a result of growth contributed to the change in cadmium tissue concentration during the depuration period. Thus, our results indicate that in Capitella sp. I sedimentbound cadmium is the major route of uptake. We found that cadmium affects starving but not fed worms, despite the fact that fed worms took up considerably more cadmium than starving worms. Our results suggest that stress associated with food limitation increases the susceptibility of worms to cadmium stress.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.