The natural abundance carbon-13 magnetic resonance spectra of estra-l,3,5(10)-triene and 17 derivatives are reported. Substituent effects upon the chemical shifts of each carbon atom are determined and discussed in terms of factors known to influence 13C chemical shifts.
The results are given in Table I and shown graphically in Figure 1. The binodal area at 15°C. is considerably smaller than at 25°C ., indicating the probability of a lower critical point at which the binodal area disappears. The total area under the two curves is strikingly similar, the only major difference being a slight reduction in the over-all solubility of the salt in water at the lower temperature.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.