Summary
Cognitive behavioural therapy for insomnia is the recommended treatment for chronic insomnia. However, up to a quarter of patients dropout from cognitive behavioural therapy for insomnia programmes. Acceptance, mindfulness and values‐based actions may constitute complementary therapeutic tools to cognitive behavioural therapy for insomnia. The current study sought to evaluate the efficacy of a remotely delivered programme combining the main components of cognitive behavioural therapy for insomnia (sleep restriction and stimulus control) with the third‐wave cognitive behavioural therapy acceptance and commitment therapy in adults with chronic insomnia and hypnotic dependence on insomnia symptoms and quality of life. Thirty‐two participants were enrolled in a pilot randomized controlled trial: half of them were assigned to a 3‐month waiting list before receiving the four “acceptance and commitment therapy‐enhanced cognitive behavioural therapy for insomnia” treatment sessions using videoconference. The primary outcome was sleep quality as measured by the Insomnia Severity Index and the Pittsburgh Sleep Quality Index. All participants also filled out questionnaires about quality of life, use of hypnotics, depression and anxiety, acceptance, mindfulness, thought suppression, as well as a sleep diary at baseline, post‐treatment and 6‐month follow‐up. A large effect size was found for Insomnia Severity Index and Pittsburgh Sleep Quality Index, but also daytime improvements, with increased quality of life and acceptance at post‐treatment endpoint in acceptance and commitment therapy‐enhanced cognitive behavioural therapy for insomnia participants. Improvement in Insomnia Severity Index and Pittsburgh Sleep Quality Index was maintained at the 6‐month follow‐up. Wait‐list participants increased their use of hypnotics, whereas acceptance and commitment therapy‐enhanced cognitive behavioural therapy for insomnia participants evidenced reduced use of them. This pilot study suggests that web‐based cognitive behavioural therapy for insomnia incorporating acceptance and commitment therapy processes may be an efficient option to treat chronic insomnia and hypnotic dependence.
The effects of milnacipran (50 mg bid) on sleep patterns of eight depressed inpatients, treated for 4 weeks, were studied during the initial (days 1-3) and terminal (days 26-28) treatment periods and compared with those obtained from three sleep recordings performed just prior to the initiation of the treatment. The clinical evolution of patients was evaluated weekly using the MADRS depression scale and the Spiegel and Norris sleep scales. Clinical improvement, shown by a mean reduction of 58% in MADRS scale scores, was accompanied by an improvement of disturbed sleep parameters. From the beginning of treatment, there was an increase in the total duration of sleep and stage II sleep, a decrease in sleep latency and an increase in sleep efficiency. Total REM sleep was not modified although, since there was an increase in total sleep time, the percent REM sleep was significantly reduced. REM latency was increased early in the study, an effect classically associated with antidepressant treatment. This study suggests that milnacipran improves disturbed sleep parameters in depressed patients without any additional disturbance at the onset of treatment.
RÉSUMÉLa plupart des auteurs s'accordent pour souligner le caractère particulièrement anxiogène des soins dentaires, notamment des extractions. Cependant, l'odontologie n'est pas la seule discipline médicale à réaliser des interventions chirurgicales sous anesthésie locale. Objectif : Effectuer une comparaison de l'anxiété préopératoire liée à un acte chirurgical dentaire à celle liée à une intervention chirurgicale, la plus proche possible sur le plan de la technique opératoire. Méthodes : Cette étude compare sur une population de 63 patients l'anxiété induite par une extraction dentaire simple effectuée dans un service hospitalier d'odontologie et par l'exérèse d'une lésion cutanée bénigne, au sein d'un service hospitalier de dermatologie. Le niveau d'anxiété est évalué à l'aide d'un questionnaire comportant différentes échelles : une échelle d'évaluation de l'anxiété-état et de l'anxiété-trait (STAI) ; une échelle évaluant les manifestations physiologiques de l'anxiété et les facteurs anxiogènes (la DFSm) ; une échelle visuelle analogique de l'anxiété (EVA). Résultats : Ils montrent que la perspective d'une extraction dentaire simple engendre une anxiété relativement faible, pas plus importante que celle précédant un acte chirurgical cutané bénin. Les femmes se révèlent plus anxieuses que les hommes à la perspective d'une chirurgie cutanée, alors qu'il n'y a pas de différence significative, selon le sexe, pour l'extraction dentaire. Conclusion : Les résultats de cette étude remettent en cause certaines notions concernant l'anxiété préopé-ratoire liée aux extractions dentaires qui semblerait davantage conditionnée par le caractère anxieux des sujets que par la symbolique particulière des soins dentaires.
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