Background The Coronavirus disease 2019 (COVID-19) pandemic continues to spread across the world. Hence, there is an urgent need for rapid, simple, and accurate tests to diagnose severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Performance characteristics of the rapid SARS-CoV-2 antigen detection test should be evaluated and compared with the gold standard real-time reverse transcription-polymerase chain reaction (RT-PCR) test for diagnosis of COVID-19 cases. Methods The rapid SARS-CoV-2 antigen detection test, Standard™ Q COVID-19 Ag kit (SD Biosensor®, Republic of Korea), was compared with the real-time RT-PCR test, Allplex™ 2019-nCoV Assay (Seegene®, Korea) for detection of SARS-CoV-2 in respiratory specimens. Four hundred fifty-four respiratory samples (mainly nasopharyngeal and throat swabs) were obtained from COVID-19 suspected cases and contact individuals, including pre-operative patients at Siriraj Hospital, Bangkok, Thailand during March–May 2020. Results Of 454 respiratory samples, 60 (13.2%) were positive, and 394 (86.8%) were negative for SARS-CoV-2 RNA by real-time RT-PCR assay. The duration from onset to laboratory test in COVID-19 suspected cases and contact individuals ranged from 0 to 14 days with a median of 3 days. The rapid SARS-CoV-2 antigen detection test’s sensitivity and specificity were 98.33% (95% CI, 91.06–99.96%) and 98.73% (95% CI, 97.06–99.59%), respectively. One false negative test result was from a sample with a high real-time RT-PCR cycle threshold (Ct), while five false positive test results were from specimens of pre-operative patients. Conclusions The rapid assay for SARS-CoV-2 antigen detection showed comparable sensitivity and specificity with the real-time RT-PCR assay. Thus, there is a potential use of this rapid and simple SARS-CoV-2 antigen detection test as a screening assay.

Although overcorrection of the abduction deformity at the midfoot remains the primary determinant of lateral forefoot overload, utilizing a graft with a larger taper may lower the incidence of lateralized forefoot pressure following correction.

Purpose Unstable posterior fracture-dislocation of the hip is determined by the wall defect or acetabular fracture index. The unstable hip is a result of inadequate posterior acetabular coverage of the femoral head from the posterior acetabular wall fracture. In order to measure total posterior acetabular coverage of the femoral head and avoid using the contralateral acetabulum as a calculation reference, the posterior acetabular arc angle of the femoral head was measured to assess stability of posterior fracture-dislocation of the hip. Methods Using coronal computed tomography (CT) scan of the normal contralateral acetabulum at the level of the widest acetabular diameter and thinnest medial wall of 60 acetabular fractures, posterior acetabular arc angles of the femoral head in intact, 20 % and 50 % defects of posterior acetabular walls were measured. The angles were measured from the acetabular centre to the thinnest medial wall and to the top, inner cortex of 80 % and 50 % posterior acetabular walls. Results Average intact, 80 % and 50 % posterior acetabular walls were 33.82±4.30, 26.88±3.33 and 16.91±2.15 mm which corresponded to 92.25 ± 11.34, 77.42 ± 10.04 and 50.63±6.58°of posterior acetabular arc angles of the femoral head. The intraclass correlation coefficient (ICC) of the measurements including correlation of conversion of posterior acetabular wall depths to posterior acetabular arc angles of the femoral head were more than 0.82 and 0.89. ConclusionsThe measurement technique of posterior acetabular arc angle of the femoral head has strong reliability. Therefore, stable or unstable posterior fracture-dislocation of the hip can be determined in terms of more than 77 degrees or less than 50 degrees of posterior acetabular arc angles of the femoral head instead of less than 20 % or more than 50 % posterior acetabular wall defect.