Summaryobjective To assess the efficacy of chloroquine in the treatment of Plasmodium vivax malaria in in Dawei District, southern Myanmar.methods Enrolled patients at Sonsinphya clinic >6 months of age were assessed clinically and parasitologically every week for 28 days. To differentiate new infections from recrudescence, we genotyped pre-and post-treatment parasitaemia. Blood chloroquine was measured to confirm resistant strains.results Between December 2002 and April 2003, 2661 patients were screened, of whom 252 were included and 235 analysed. Thirty-four per cent (95% CI: 28.1-40.6) of patients had recurrent parasitaemia and were considered treatment failures. 59.4% of these recurrences were with a different parasite strain. Two (0.8%) patients with recurrences on day 14 had chloroquine concentrations above the threshold of 100 ng ⁄ ml and were considered infected with chloroquine resistant parasites. 21% of failures occurred during the first 3 weeks of follow-up: early recurrence and median levels of blood chloroquine comparable to those of controls suggested P. vivax resistance.conclusions Plasmodium vivax resistance to chloroquine seems to be emerging in Dawei, near the Thai-Burmese border. While chloroquine remains the first-line drug for P. vivax infections in this area of Myanmar, regular monitoring is needed to detect further development of parasite resistance.
The Hponkanrazi Wildlife Sanctuary, North Myanmar and three contiguous protected areas, comprise some of the largest expanses of natural forest remaining in the region. Demand for wildlife products has resulted in unsustainable exploitation of commercially valuable species resulting in local extirpation of vulnerable species. Camera trap, track and sign, and questionnaire-based surveys were used to examine (a) wildlife species targeted by hunters, (b) the importance of wild meat for household consumption, and (c) the significance of hunting as a livelihood activity for resident villages. Certain commercially valuable species highly preferred by hunters were either completely absent from hunt records (tiger, musk deer and otter) or infrequently obtained during actual hunts (bear, pangolin). Species obtained by hunters were commonly occurring species such as muntjacs with low commercial value and not highly preferred by hunters. Fifty eight percent of respondents (n = 84) indicated trade, 27% listed subsistence use and 14% listed human-wildlife conflict as the main reason for hunting (n = 84). Average amount of wild meat consumed per month is not significantly higher during the hunting season compared to the planting season (paired t-test, P > 0.05). Throughout the year, the average amount of fish consumed per month was higher than livestock or wild meat (Friedman test, P < 0.0001). Hunting is driven largely by trade and wild meat, while not a critical source of food for a large number of families could potentially be an important, indirect source of access to food for hunting families. Findings and trends from this study are potentially useful in helping design effective conservation strategies to address globally prevalent problems of declining wildlife populations and dependent human communities. The study provides recommendations to reduce illegal hunting and protect vulnerable species by strengthening park management through enforcement, increasing the opportunity costs of poaching, establishing no-take zones and research to determine the economic significance of hunting for livelihoods.
Hunting for subsistence and trade constitute a major threat to wildlife populations within and outside protected areas in Myanmar. We examined hunting patterns in a forested landscape adjoining the Hkakaborazi National Park in north Myanmar with the aim of generating recommendations to manage hunting. The results described here focus on two issues: the significance of proximity to settlements and markets for prey abundance, and the influence of relative abundance and intrinsic preference on prey offtake. We used strip transect and camera trap surveys to generate relative abundance indices and overall encounter/capture rates for commonly hunted species at four sites that differed in their proximity to settlements and large trading towns. Questionnaires were used to obtain meal records and information on hunting. Encounter and capture rates for hunted species appear to be inversely related to proximity to villages as well as to large, commercial towns. Hunting is indiscriminate, with offtake determined largely by relative abundance rather than intrinsic preference or legislation. Specific management and policy recommendations include the need to monitor the impacts of hunting on vulnerable species, the demarcation of no-take areas, and modification of the legal framework for wildlife conservation.
We present a morphological and molecular assessment of the Microhyla fauna of Myanmar based on new collections from central (Magway Division) and northern (Kachin State) parts of the country. In total, six species of Microhyla are documented, including M. berdmorei , M. heymonsi , M. butleri , M. mukhlesuri and two new species described from the semi-arid savanna-like plains of the middle part of the Irrawaddy (Ayeyarwady) River Valley. We used a 2 481 bp long 12S rRNA–16S rRNA fragment of mtDNA to hypothesize genealogical relationships within Microhyla . We applied an integrative taxonomic approach combining molecular, morphological, and acoustic lines of evidence to evaluate the taxonomic status of Myanmar Microhyla . We demonstrated that the newly discovered populations of Microhyla sp. from the Magway Division represent two yet undescribed species. These two new sympatric species are assigned to the M. achatina species group, with both adapted to the seasonally dry environments of the Irrawaddy Valley. Microhyla fodiens sp. nov. is a stout-bodied species with a remarkably enlarged shovel-like outer metatarsal tubercle used for burrowing and is highly divergent from other known congeners ( P -distance≥8.8%). Microhyla irrawaddy sp. nov. is a small-bodied slender frog reconstructed as a sister species to M. kodial from southern India ( P -distance=5.3%); however, it clearly differs from the latter both in external morphology and advertisement call parameters. Microhyla mukhlesuri is reported from Myanmar for the first time. We further discuss the morphological diagnostics and biogeography of Microhyla species recorded in Myanmar.
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