To investigate the expression of High Mobility Group Box 1 (HMGB1) and Heat Shock Protein-70 (HSP-70) during orthodontic tooth movement (OTM) after (-)-Epigallocatechin-3-Gallate (EGCG) in East Java Green Tea (Camelia Sinensis) Methanolic Extract (GTME) administration in vivo. Material and Methods: 28 Wistar rats (Rattus Novergicus) was used and divided into 4 groups accordingly: K-without EGCG and OTM; K+ with OTM, without EGCG for 14 days; T1with OTM for 14 days and EGCG for 7 days; treatment group 2 (T2) with OTM and EGCG for 14 days. OTM animal model was achieved through the installation of the OTM device by means of NiTi close coil spring with 10g force placed between the first incisor and first maxillary molars. The samples were terminated on Day 14. The pre-maxillary was isolated for the immunohistochemical examination. Analysis of Variance (ANOVA) then continued with Tukey Honest Significant Difference (HSD) (p<0.05) was performed to analyze the data. Results: The highest HMGB1 and HSP-70 expression were found in the K+ group pressure side, meanwhile the lowest HMGB1 and HSP-70 expression were found in K-group tension side in the alveolar bone. There was a significant decrease of HMGB1 and HSP-70 expression in T2 compared to T1 and K+ with significant between groups (p<0.05; p=0.0001). Conclusion: The decreased expression of HMGB1 and HSP-70 in alveolar bone of OTM wistar rats due to post administration of GTME that consisted EGCG.
Background: Patients with mandible deviation often have idiopathic scoliosis, which might affect the result of orthodontic and orthopaedic treatment. Orthodontic treatment not only focuses on aesthetic and functional but also orthopaedic stability. A thorough examination is needed to obtain orthopaedic stability by evaluating the occlusion and posture to establish the best strategy of treatment and interdisciplinary approach. Purpose: This study was conducted to assess the correlation between mandible deviation and idiopathic scoliosis. Methods: This is a descriptive-analytic study with a cross-sectional approach. From 60 samples, 35 patients were chosen based on the inclusion criteria of the total sampling technique. Patients were referred to have skull posteroanterior (PA) and a thoracolumbar PA radiograph taken. Skull PA radiographs were analysed with Grummon’s method using the Orthovision program. Cobb’s angle analysis was used by the radiologist to analyse the thoracolumbar PA radiographs. The data gathered was then further analysed using the Spearman test and the Crosstabs test, using SPSS 23.0. Results: Correlation between mandible deviation and the severity of idiopathic scoliosis is not significant (p=0.866). The direction prevalence of mandible deviation towards Cobb’s angle is 54.3% to the right and 45.7% to the left. All patients with mandible deviation have Cobb’s angle. Conclusion: There is no correlation between mandible deviation and the severity of idiopathic scoliosis. However, many cases showed that the direction of mandible deviation and of idiopathic scoliosis is the same.
Introduction > With conventional anchorage, it is usually hard to accomplish a satisfactory result with an absolute anchorage, and this limitation could be resolved by the usage of mini-screw. The successful rate of miniscrew usage depends on its stability, which was determined by its length, bone density, cortical bone thickness, the insertion technique, the insertion angle, and the applied loads. Objective > To observe the effect of miniscrew length and bone density on anchorage resistance. Material and methods > Thirty pieces of miniscrew with 1.6 mm in diameter were divided into three groups based on its length (n = 10): 10 mm (L), 8 mm (M), and 6 mm (S). Each group was further divided into 2 subgroups: to be planted in optimal density bovine ribs (L1, M1, S1) and to be planted in low-density bovine ribs (L2, M2, S2). The density of bovine ribs was measured by CBCT. After the insertion of miniscrews based on respective groups, tensile test was done by means of Autograf Univerval Testing Machine to measure its stability. The data recorded was analysed using the Least Significant Difference (LSD) Fisher's test. Results > The results of this study showed that L1 provided the greatest stability than other groups. On the other hand, the least stability was found in S2. Conclusion > The length of miniscrew and the density of bone affect the stability of miniscrew. In bone with optimum density, 10 mm and 8 mm miniscrew equipped good anchorage resistance while in bone with low-density only 10 mm miniscrew provided favourable anchorage resistance. Mots clés Densité osseuse Longueur des mini-vis Stabilité Résumé Effets de la longueur des mini-vis et de la densité osseuse sur la résistance d'ancrage : une étude in vitro
This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
Background: Debonding aims to remove orthodontic appliances from the patient's teeth and cleanse all residual adhesive material on the surface of the tooth to restore surface conditions such as before orthodontic treatment. Damage may occur after debonding process. Removal of the remaining adhesive material has a major effect on the enamel surface conditions, the researcher wants to know the effect of cleaning adhesive material using Tungsten carbide 12 flute burs, Arkansas stone bur on the enamel surface Purpose: To determine the effect of cleaning the remaining adhesive material using Tungsten carbide 12 flute burs and Arkansas stone bur Against the Surface of the Enamel. Method: This study was experimental laboratory (in vitro study) with 4 groups division, first control group was tooth before bracket was installed, group 2 was done debonding without cleaning of residual adhesive, group 3 was done adhesive cleansing with Arkansas stone and group 4 was done adhesive cleaning with tungsten carbide 12-flutted Result: Showing that the use of 12-flutted tungsten carbide was able to clean enamel surfaces with the most delicate results and did not cause cracks or cracks on enamel surface Conclusions: The best method to clean the remaining adhesive is using 12-flutted tungsten carbide bur using contra angle high speed and with adequate water flow and sprays to prevent increasing of temperature that damage dental pup.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.