Background and aims: This study examined the lived experience of individuals who underwent ibogaine treatment for an opioid use disorder. Methods: Semi-structured interview questions probed for potential changes in predetermined categories derived from a literature review. Participants' experiences with ibogaine were analyzed for commonalities and emergent themes. Results: Categories that emerged revealed themes about subjective neurological and physical effects, auditory and visual phenomena, impact on withdrawal and craving, and shifts in outlook on self and life. Conclusion: Ibogaine treatment provides a subjectively powerful physiological, emotional, and psychological experience, attenuates opioid withdrawal, and results in a more optimistic outlook on self and life.