Accession no.Y00433 cDNAs encoding human glutathione peroxidase were isolated from a liver library prepared as described (1) by hybridization with a synthetic oligonucleotide (shown with the closed bar) to the 5' and 3' ends of the mouse genomic DNA sequence reported elsewhere (2). The sequence of 1134 bp minus the poly A tail of the longest cDNA clone is presented below with the predicted amino acid sequence. An asterix indicates the selenocystein at the position of the in-frame TGA codon. Comparison of our data with those of mouse (2) revealed 84% homology at the nucleotide level and 87% homology at the amino acid level.
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