A solvent-free and scalable method was developed for the preparation of soybean-oil-based polyols by a thiol–ene photo-click reaction with a homemade photochemical reactor. The effect of reaction parameters, including photoinitiators, reaction time, molar ratios of thiols to carbon–carbon double bonds, and power of the mercury lamp, on the structures of the resulting polyols was investigated. The mechanism of the thiol–ene photo-click reaction was also discussed. On the basis of these novel polyols, several polyurethanes were prepared using different diisocyanates (aliphatic, cycloaliphatic, and aromatic isocyanate) and characterized. The resulting polyurethane films possess good performance, including the highest glass transition temperature of 41.3 °C, tensile strength of 15.7 MPa, and elongation at break of 471.0%.

In this study, flavoured tea tree oil (TTO)-loaded antibacterial microcapsules were developed based on the complex coacervation of sodium alginate (SA) and a quaternary ammonium salt of chitosan (HACC).

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In this work, a 3D printed double‐network (DN) hydrogel scaffold is designed with chitosan (CS) and polyvinyl alcohol (PVA) as the framework matrix. The addition of PVA into the CS‐based hydrogel clearly enhances the mechanical properties and lowers the swelling behaviors of the hydrogels. The crosslinking of CS with genipin can perform the pre‐crosslinking to improve the viscosity and 3D printability of the hydrogel precursor, while increasing the PVA content results in lowering the viscosity and 3D printability of the pre‐crosslinked hydrogel. The antibacterial property results of the DN hydrogel display that the hydrogel have favorable long‐lasting antibacterial ability. The appropriate pre‐crosslinked hydrogel with the CS/PVA mass ratio of 3:10 and pre‐crosslinking time of 7 h is used for 3D printing to prepare the 3D printed porous DN hydrogels. Moreover, the anti‐tumor drug doxorubicin (DOX) is loaded into the 3D printed porous DN hydrogels and the in vitro release study displays the sustainable drug release behavior. And the DOX release from hydrogel scaffold can be adjusted by the pH value of release environment. All of the results indicate that the porous DN CS/PVA hydrogel scaffolds have great application potential for tissue regeneration.

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