Introduction: Despite high rates of mortality and morbidity due to preterm delivery, none of the diagnostic and biochemical tests could help to accurately identify the cases at risk of preterm delivery. Objectives: Since ferritin is an acute phase reactant, this study aimed to evaluate serum ferritin levels in women with preterm and term delivery. Methods: This study was conducted on 150 women with preterm delivery (50 cases in each of the groups 24-30, 30-34, and 34-37 weeks of pregnancy), 150 women with term delivery, and 150 pregnant women who were between 24-37 weeks of pregnancy (same as preterm delivery groups). Results: The mean ferritin level in all preterm groups was significantly higher than that in the term group, but there was no difference among the preterm groups. In addition, ferritin level in each preterm group was significantly higher than those in the normal pregnancy group at the same gestational age. In preterm deliveries, ferritin levels were significantly higher in cases with prelabor rupture of membranes (PROM) or with a prolonged leakage (longer than 12 hours). In addition, in patients with PROM or prolonged leakage, ferritin levels were significantly higher in preterm deliveries than in term deliveries. A ferritin level of 37.5 ng/mL recognized as the best cut-off for preterm delivery, as compared with term delivery, and its sensitivity, specificity, and diagnostic accuracy was 78.7%, 68.7%, and 73.6%, respectively. Conclusion: The findings of the present study showed that serum ferritin level can be used to find patients at risk of preterm delivery.
Introduction: Episiotomy is a surgical incision at the vaginal opening performed in the second stage of labor during childbirth. The purpose of performing an episiotomy is to increase the size of the soft tissue of the pelvis floor and prevent damage to the perineum, facilitate delivery, and reduce the time during childbirth. Objectives: This study aimed to determine the effect of Teucriumpolium ointment on wound healing in primiparous women. Patients and Methods: This triple-blinded clinical trial was conducted on 84 primiparous women referred to Mahdieh hospital in Tehran. Participants randomly received 2% T. polium ointment and placebo. The first time the ointment was started 24 hours after delivery and continued twice a day for 10 days. Wound healing rate was measured by redness, edema, ecchymosis, discharge, and approximation (REEDA) scale on days 1, 5, and 10 postpartum. The data were analyzed using SPSS version 23. Results: The results were performed on 84 women, 43 people using T. polium ointment and 41 people using placebo ointment. There was no significant difference between the two groups regarding obstetrics and demographic characteristics at the beginning of the study. The mean scores of REEDA in the T. polium group in the first 12 hours, days 5 and 10 were significantly different from the placebo group (P<0.001). Conclusion: Wound healing following episiotomy can be accelerated due to antibacterial, anti-inflammatory, and antiseptic properties of T. polium ointment. Trial Registration: The trial protocol was approved by the Iranian registry of clinical trial (#IRCT20100130003226N18; https://en.irct.ir/trial/40004, ethical code# IR.SBMU.RETECH.1398.055).
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.