Introduction: The whole world is on the brink of collapse due to the outbreak of COVID-19 with no solution to treat these cases with any specific drug. Extensive search for the Vaccine or effective treatment is going on while alarming infection and death toll is rising every day. Aim: The study will compare the effect of Ivermectin with Doxycycline and Hydoxychloroquine with Azythromicin on a selective group of COVID -19 positive patients. Method: This is a comparative study that included 400 patients of COVID 19 positive patient who were divided in to two groups. Group- A Received Ivermectin with Doxycycline and the other group- B received hydroxichloroquine(HCQ) with azithromycin. Result: Viral clearance is 132 ( 66%) on day 5 and 167( 83.5% ) on day 6. Among them 33(16.5%) remain PCR positive after 6th day of Ivermectin ingestion in Group A. Whereas there is154 ( 77.0%) viral clearance at 11th day and 163(81.5%) viral clearance at 12th day of Hydroxychloroquine ingestion in Group B. Among them 37 (18.5%) remain PCR positive after 12 day in group B. The P value is 0.000427 which is significant considering 5th day viral clearance of Ivermectin ingestion and 11th day of Hydroxychloroquine ingestion. But considering 6th day and 12th day the P-value is 0.59 which is not significant. Conclusion: It appears Ivermectin and Doxycycline is safeand effective combination drug therapy in COVID- 19infected patients but need further extensive study to find out the scope of application on other groups of patients. J Bangladesh Coll Phys Surg 2020; 38(0): 5-9
This descriptive type of cross sectional mixed method study was conducted with four specific objectives to understand the perception, area, ways and barriers in socialization of undergraduate medical students in Bangladesh. The study was conducted in 8 (eight) medical colleges of which 6 (six) are public and 2 (two) are private. The study was conducted for one year from July 2017 to June 2018. Total 712 student of final phase participated in the study. In- depth interview was conducted with teachers. Convenience sampling technique for selection of the students whereas medical colleges were selected purposefully. Study revealed that most of the asked parameters related to patient care and humanistic attitude was taught to the undergraduate medical students of the selected medical colleges in Bangladesh. There are few concerns though in some area like number of role models and presence of negative role models among the teachers. Contents, aim and objectives of the current curriculum is vastly unknown to teachers. A conscious attempts to be made to transform medical students in a positive manner. Teachers should be selected following a proper career planning and they should undergo some kind of courses before deployment which would give them an understanding on teaching methodology and capability to foster ethically compatible as well as technically skill medical students of current era. Bangladesh Journal of Medical Education Vol.10(1) 2019: 14-19
Background: The unprecedented global pandemic caused by SARS-CoV-2 creates considerable psychological problems among the health care workers (HCW). The present study aimed to determine the predictors of psychological impact (in terms of depression, anxiety and stress) among the HCWs exposed Covid-19 cases in Combined Military Hospital (CMH) Dhaka. Methods: This cross-sectional study was conducted at CMH Dhaka among purposively selected 390 HCWs. Data were collected through face-to-face interview using a pre-tested semi-structured questionnaire with validated and reliable tools. The study was conducted in the Combined Military Hospital Dhaka from 15 July 2020 to 30 September 2020. Results: Among the 390 respondents, 21.6%, 43.1% and 24.1% had depression, anxiety and stress symptoms, respectively. Being married (OR=0.391, 95% CI=0.160-0.953), graduate (OR=2.977; 95% CI=1.181-7.509) and attending 41-80 patients per day (OR=1.996; 95% CI=0.965-4.125) was significantly associated with depressive symptoms. In respect of anxiety, being graduate (OR=2.788, 95% CI=1.228 -6.333) and HSC qualified (OR=2.714, 95% CI=1.073-6.869), staying in family accommodation (OR=2.720, 95% CI=1.136 - 6.516), with nuclear family (OR=0.459, 95% CI=0.281-0.750), smoker (OR=1.827, 95% CI=0.987 - 3.384), doctor (OR=0.362, 95% CI=0.173- 0.758), having service length <20 years (OR=2.229, 95% CI=1.158 - 4.289), service in current place of posting for <20 months (OR=0.460, 95% CI=0.241-0.880), attended 41-80 patient daily (OR=1.720, 95% CI=0.933 - 3.169) and performing overtime duty (OR=2.568, 95% CI=1.609-4.099) were significantly associated with anxiety symptoms. Being graduate (OR=2.249, 95% CI=0.866-5.844), with nuclear family type (OR=0.423, 95% CI=0.249-0.721), having duty place at emergency (OR=2.135, 95% CI=0.902-5.053), being a nurse (OR=0.364, 95% CI=0.162-0.819), having service length <10 years (OR=2.570, 95% CI=1.207-5.472) and performing overtime duty (OR=2.214, 95% CI=1.3101-3.742) were significantly associated with stress symptoms. Conclusion: Psychological problems among the HCW found very common in our study which needs psychological crisis interventions to protect the mental health of HCWs. JOPSOM 2021; 40(1): 1-13
Introduction: The unprecedented global pandemic that sweeps the planet is caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infections. To combat this pandemic, the clinical presentation as well as other epidemiological characters need to be understood clearly. Objective: To describe epidemiological and clinical characteristics, management, and outcomes of Covid-19 patients attended at the Combined Military Hospital (CMH), Dhaka. Materials and Methods: This cross sectional study was conducted at CMH Dhaka from 15 April 2020 to 31 May 2020 among purposively selected 237 COVID-19 positive patients. Data collection was done by face-to-face interview using semistructured questionnaire and medical record review. Results: Highest numbers of the respondents were in the age group of 31-40 years (37.1%) with male predominance (83.1%). About 95.6% were Muslim and 58.6% were educated up to secondary level. About 87.8% had contact with a confirmed case and having 47.7%, 37.2% and 15.1% cardiovascular, endocrine and respiratory co-morbidities respectively. Fever (34.6%) was the common presenting symptoms followed by cough (22.9%), sore throat (10.6%). Radiologically about 7.2% developed bilateral pneumonia and 5.5% having lung involvement in HRCT. Almost half of the patients (48.9%) received Ivermectine and Doxicycline as treatment. Average duration of hospital stay was 14.61 (±4.29) days. About 17.7% showed neutrophilia, 30.0% positive D-dimer test, 22.4% either sepsis or systemic infection in procalcitonin estimation, 28.3% with increased ferritin, 28.7% positive C reactive protein, 21.1% with increased LDH. Conclusion: The study findings will help the clinicians and medical administrators to understand the magnitude of the disease and take appropriate measures for its prevention. JAFMC Bangladesh. Vol 17, No 2 (December) 2021: 22-28
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