Using the adsorption properties of polyvinylpyrrolidone and the antitrombocytic properties of acetylsalicylic acid in operation, a drug coating was applied to a metal stent by an electrochemical method. Optimal conditions of electrochemical deposition of drug coatings on metal surfaces are selected. The obtained drug coating was evaluated and the thickness of the drug coating was calculated. Drug-coated stents are the most significant innovation in invasive cardiology of the early 21st century. In this regard, methods that allow the rapid, effective and long-term restoration of blood circulation in a damaged vessel are being actively developed. Stenting coronaries that nourish the heart is a sparing intravascular surgery with expansion of stenosed or occluded areas of the arteries by the stent. The mesh structure allows it to be delivered to the installation site in a compressed state, and in place – to expand to the size required by the vessel. Since the implant is a foreign body, the introduction of a stent provokes the activation of blood coagulation mechanisms, which is the cause of restenosis – repeated blockage of the vessel. To reduce the risk of restenosis, a drug coating is applied to the stent to prevent blood clots from forming in blood vessels.
Problems of detecting sweat and grease deposits on porous surfaces are common for forensic practice, and usually, they are successfully resolved with the help of chemical methods. Meanwhile, the interaction process in the system “porous surface – deposit – chemical agent" concerning clarification and identification of the trends within chemical reaction is not reviewed in literature sufficiently. For more comprehensive research of this process, the authors of the article have conducted multiple experiments on the ninhydrin reaction with the sweat and grease of the deposits, analyzed the interaction of the chemical agent with the sweat and grease, with the properties of porous (paper) materials using electron microscopy, and also looked into the display features of pore and edgeoscopic signs in the deposits under different storage conditions.As a result of the research, it is shown that such parameters of deposits carriers (paper) as porosity and hydrophilic properties and ambient humidity as well as the time of storage have a significant influence on the process of detecting the sweat and grease deposits on porous surfaces and their quality.
Studies of adsorption properties of carbon nanotubes with respect to inorganic molecules have been carried out. Theoretical quantum-chemical calculations of the interaction of the most common impurity molecules in water with carbon nanotubes were made. Analysis of modern water purification filters shows the general disadvantage of all modern filters – they clean water only from a certain type of pollution. In order to clean water from a wide range of different pollutants, it is necessary to carry out multistage purification, with different types of filters, which is very resource intensive, and takes quite a long time. Using carbon nanomaterials as filters will solve this problem. For the study, the most common inorganic substances were chosen, which are most often found in drinking water: calcium chloride CaCl2, magnesium chloride MgCl2, sodium chloride NaCl, calcium carbonate CaCO3, magnesium carbonate MgCO3, calcium sulfate CaSO4, magnesium sulfate MgSO4. Processes of adsorption interaction of selected inorganic impurity molecules to the surface of single-layer carbon nanotubes of type (6,6) were investigated. Surface profiles of potential energy of interaction of molecules (calcium, magnesium and sodium salts) with surface of carbon nanotube are constructed. The positive effect of carbon nanostructures on the process of water purification from inorganic impurities is shown, meaning the possibility of using CNT as a filter for water purification.
Publications on the study of materials suitable for the manufacture of coronary stents, as well as the properties of polyvinylpyrrolidone and acetylsalicylic acid were studied. The causes of restenosis are considered. The evaluation of the obtained coating applied by electrochemical method is given. Corrosion tests of the studied samples with a coating by the method of polarization resistance were carried out. The dependence of the corrosion resistance of the material on the concentration of acetylsalicylic acid in the composition of the drug coating was revealed.
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