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Port-wine stain (PWS) is a congenital capillary malformation commonly found in the head and neck. With an incidence of 0.3%-0.9% in the newborns, this pathological condition affects males and females equally. 1,2 PWS lesions first appear as pink or red macules that do not undergo spontaneous involution and may progressively darken to reddish purple. 3 The lesions grow proportionately with age and can lead to the formation of papules and nodules or may develop into hypertrophic PWS. 4 Aside from cosmetic disfigurement, PWS hypertrophy may also impair sight, speech, nasal breathing, and hearing. 5 PWS is also associated with two uncommon syndromes: Sturge-Weber syndrome (SWS) and Klippel-Trenaunay syndrome (KTS). 6 SWS is a neurocutaneous disorder characterized by PWS usually affecting one hemiface along one or more trigeminal

Introduction Port-wine stain (PWS) is a progressive capillary malformation that does not resolve spontaneously without treatment. Pulsed dye laser (PDL) is currently the gold standard treatment for PWS, although it is difficult to attain complete clearance and recurrences are common. This study determined the cost-effectiveness of PDL treatment among Thai patients with facial PWS. Methods This was a retrospective chart review of 109 Thai patients with facial PWS and treated with PDL at Siriraj Hospital, Thailand from January 2008 to December 2017. The primary outcome of the study was the cost-effectiveness of PDL treatment in the clinical improvement of facial PWS. Results Ten PDL treatment sessions will have an expected clinical improvement of 60%. At the 10th treatment, the marginal incremental improvement with respect to visit is approximately equal to one. The succeeding treatment sessions will only give an additional improvement of 5–10%. Conclusion A total of 10 PDL treatment sessions was considered cost-effective as it can achieve 60% clinical improvement among Thai patients with facial PWS.

Introduction Port-wine stain (PWS) is a congenital malformation that does not resolve spontaneously and can cause a physiological or psychological burden to the patients. At present, most of the studies done on PWS are focused on the treatment rather than the quality of life and psychological effects of the disease. Material and Methods A comprehensive literature search was done in MEDLINE using PubMed database, Embase ® , and Cochrane. All observational studies were included in this review. Results A total of 17 relevant articles with 2,135 PWS patients were included in this review. There were 36 measurement tools used to assess the quality of life and the psychological effects among PWS patients. The results showed that patients with facial PWS had a significant negative effect on their quality of life and had also suffered from psychological disabilities. The PWS lesion tends to worsen with age and may cause further adaptation problems towards the social environment, especially in children. Conclusion Early treatment, psychological assistance, and patient support are the key management in improving the quality of life of patients with PWS. Quality of life must be regularly assessed together with the improvement of treatment.

Purpose The purpose of this paper is to propose a cradle-to-cradle (C2C) zero discharge production planning system with a fuzzy hybrid optimization model that uses fuzzy comprehensive evaluation to establish fuzzy indicators, and then defuzzify the fuzzy indicators to construct a fuzzy multiobjective programming (FMOP) model. Design/methodology/approach The FMOP model pursues overall satisfaction using a particle swarm optimization algorithm to produce the best output values for the maximum waste paper recovery rate, the condensate reuse quality and minimum total cost of the zero discharge production planning system. Findings Recovered waste heat is seldom recycled and consumed in Taiwan. There is a need to capture and utilize heat recovery and use it in the production process supply. In contrast, waste materials are used as resources to perform waste paper recovery and recycle the waste heat of evaporation collection in the production process. Originality/value This paper develops a system to establish the best output value for an overall high satisfaction level. According to the results, the waste paper recovery rate is 99.8 percent, condensate reuse quality water is 102.6 tons and the total cost of the zero discharge production planning system is NT$1,312,012.

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This study proposes a multi-objective production programming model which is established for systematic sorting and remanufacturing second-hand clothes and the objectives are twofold: (1) minimizing the remanufacturing cost to maintain the competitiveness of second-hand clothing industry and (2) maximizing the recycle rate to reduce the environmental impact from the disposed clothes. Previous studies are lacking to involve the features of second-hand clothing recycled from reuse to recycle in optimizing both the remanufacturing costs and recycle rate. The consequential final destination of consumers’ second-hand clothes is either resold, donated, or disposed of. This study applied sensitivity analysis by varying production cost and new material cost are conducted to evaluate the suitability of three different types of sorting methods for second-hand clothes before let them entering the remanufacturing processes on (1) categories the used clothes; (2) worn-out conditions (high, medium, low), and (3) clothes materials (cotton, linen, wool, silk, artificial fiber). The results show that the first sorting method by clothing categories outperforms the other two methods in maximizing the recycling rate. The second sorting method by worn-out condition generates a minimal remanufacturing cost. The recycling scenarios are simulated to verify the applicability of the proposed programming model with respect to the three sorting methods. The results show that Taiwan exhibited superior the recycle rates and Bangladesh had lower remanufacturing costs by adopting the sorting method by clothes materials.