Predictive factors of good aesthetic results in conservative surgery for breast cancer Predictive factors of good aesthetic results in conservative surgery for breast cancer Fatores preditivos para um bom resultado estético em cirurgias conservadoras por câncer de mama ABSTRACT Background: The aim of conservative surgery for treatment of breast cancer is obtaining satisfactory aesthetic results. Segment-based surgery, which must be followed by radiotherapy (RT), is considered the treatment of choice for most breast cancer patients. Single-dose intraoperative radiation in the tumor bed (IORT) is a promising radiation technique that is more rapid than conventional RT and less exhausting for the patient. The aim of this study was to evaluate the final aesthetic results of patients who had undergone conservative surgery and treatment for early-stage breast cancer consisting of primary closure of the operative wound and use of adjuvant radiotherapy, either conventional RT or IORT, and assess the impact of several variables on the results. Methods: Primary closure of the operative wound after conservative breast cancer treatment was performed in 66 patients. The patients were evaluated and photographed and their data collected from medical records. Results: Some degree of asymmetry was observed in 40.4% of patients. The surgically treated breast frequently appeared more aesthetically pleasing than the healthy breast, especially in patients with large breasts (P = 0.052), in whom resection of the upper quadrants improved the degree of ptosis and thus improved the appearance of the treated breast (P = 0.002 and P= 0.001, respectively). Use of periareolar incision (P = 0.008) was found to be a predictor of good aesthetic results while the comorbidity of diabetes mellitus and the use of chemotherapy were found to be predictors of poor results (P = 0.046 and P = 0.073, respectively). Conclusions: Some degree of asymmetry often results in patients for whom remodeling of mammary tissue is not possible. The factors of use of periareolar incision, large breast volume, and tumor location in one of the upper quadrants are predictors of a good aesthetic outcome, while use of chemotherapy, diabetes mellitus, and tumor location in the lower quadrants are negative predictors. Use of IORT yields aesthetic outcomes comparable to those of conventional RT in terms of extent of scarring.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.