Our results indicate that there is no genotoxicity and oxidative stress in neonates and 6 days rats. However, the RCC had the highest concentration of CP that do not seem to be a consequence of oxidative stress. This study is the first to demonstrate the use of UHF-EMR causes different damage responses to proteins in the LCC and RCC.
Objetivo: Avaliar o estado nutricional de crianças e adolescentes na admissão em unidade de terapia intensiva pediátrica de um hospital público de referência.Materiais e Métodos: Estudo transversal que avaliou 277 pacientes, de 0 a 19 anos que foram admitidos na unidade de terapia intensiva pediátrica, nas primeiras 72 h de internação, no ano de 2013. As variáveis avaliadas, a partir dos prontuários, foram as medidas antropométricas de peso e estatura. Para verificar a associação do estado nutricional com as demais variáveis, utilizou-se o teste qui-quadrado, sendo considerado significativo p<0,05.Resultados: Entre os 277 pacientes, 53,4% (n=148) eram do sexo masculino. Encontrou-se 10,5% (n=21) de desnutrição, 20,1% (n=40) de excesso de peso e 69,34% (n=138) de eutrofia. Destaca-se, que a desnutrição foi mais prevalente entre os menores de 2 anos, enquanto o excesso de peso foi maior na faixa etária de 2 a 10 anos. Em 28,79% (n=57) da amostra foi encontrado baixa estatura, com maior prevalência entre os menores de 2 anos (p<0,001), podendo estar associado ao elevado número de prematuros na amostra (n=26, p=0,003).Conclusão: Na admissão de crianças e adolescentes internados em unidade de terapia intensiva pediátrica, desnutrição foi o estado nutricional menos prevalente quando comparamos com outros estudos. O número expressivo de prematuros pode estar associado à alta prevalência de baixa estatura encontrada.
Background Viral bronchiolitis is a common lower respiratory infection during infancy. 50% of infants with acute Bronchiolitis develop Post bronchiolitis wheezing (PBW) that may cause childhood asthma. Vitamin A deficiency impairs epithelial integrity, systemic immunity and increases the severity of childhood respiratory infections such as RSV. In this study the effect of vitamin A in improving PBW has been evaluated. Methods This was a double blind pilot trial on 84 patients aged 2 to 12 months old who were admitted in Emam Sajad Hospital in Yasuj (Iran) from October 2012 to October 2013. The patients were diagnosed by history, physical examination and chest x-ray by a paediatrician. The 84 individuals were put in case and control groups (42 in each group). The case group received 5000 IU/kg Vitamine A intramascularly, plus cold and wet oxygen, and beta 2 agonist (ventolin) by nebulizer, and the control group received the same except vitamin A.1,2 and 3 weeks after treatment the patients were examined by the same paediatrician and were compared based on severity of wheezing, and response to the treatment (decrease in wheezing, distress and cough). Findings The diferences of demographic data and severity of wheezing were not significant between the groups before treatment. There were significant differences in response to treatment between two study groups after 1, 2 and 3 weeks following treatment (p = 0.045, p = 0.001 and p = 0.001 respectively). No side effects were seen during and after the course of treatment. Conclusion Usual treatments together with Vitamin-e A have stronger effect on reducing post bronchiolitis wheezing, compared with usual treatments alone. Objective To investigate the clinical characteristics and analyse risk factors for severe respiratory syncytial virus (RSV) infection in hospitalised infants with acute lower respiratory tract infections (ALRIs). Methods A retrospective review of the medical records of infants with RSV-associated ALRIs between March 1st, 2011 and February 29th, 2012 was done. Results Among 913 RSV-associated ALRI infants, there were 288 severe infants (31.5%). The severe cases accounted for 4.2% of the hospitalised children and gave a hospital RSV mortality rate of 1.0%. The occurrence of severe RSV infection had a seasonal variation, with a peak in winter (45.6%). The proportions of cases with tachypnea, apnea, cyanosis, and fine rales were significantly higher in the severe ALRIs group (all p < 0.001). The incidences of bronchitis, pneumonia and readmission in the severe group were higher than those in the nonsevere infants during the one-year follow-up (all p < 0.001). Multivariate logistic regression determined the factors increasing the risk of severe RSV infection were: low-birth-weight [ Background The study aim was to validate a specific nutritional risk screening tool for patients with cystic fibrosis (CF) based on clinical variables, anthropometric parameters, and dietary intake. Methods Cross-sectional study compared present nutritional screening tool and ...
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