A 59-year-old white man with a history of orthotopic liver transplant for cryptogenic cirrhosis developed diabetes 1 year post-transplant. His post-transplant immunosuppression regimen consisted of tacrolimus, mycophenolate, and prednisone. The patient presented to the clinic for diabetes management, at which time he was taking glipizide extended release 5 mg daily. The patient checked his blood glucose two times daily (premeal average 170 mg/dL, postmeal average 184 mg/dL; Table 26.1). At this time, the hemoglobin A1c (HbA1c) was 5.8% and the hematocrit was 39.9%. Sitagliptin 100 mg daily was added to the glipizide.
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