Background. Aggressive forms of periodontitis are a group of periodontal diseases characterized by rapid development, significant bone loss, few clinical manifestations, weak inflammatory and immune response, a small number of microorganisms, not proportional to the severity of destruction. According to modern ideas about the etiology of aggressive forms of periodontitis, the main reason for their development – the penetration of periodontal tissue Aggregatibacter actinomycetemcomitans. Therefore, aggressive forms of periodontitis may require adjunct antibacterial therapy. Objective ― to determine and analyze the most effective methods of antibiotic therapy in patients with aggressive forms of periodontitis. Methods. A literary review of the studies of Russian and foreign scientists on the development of approaches to improving the effectiveness of antibiotic therapy of aggressive forms of periodontitis in patients, using scientific search library databases PubMed, Medline, Cochrane, Elibrary. The main selection of materials was carried out by keywords. 37 publications were found. Results. The review describes the main methods of modern antibiotic therapy of aggressive forms of periodontitis, the main advantages of antibacterial drugs. Conclusion. In modern periodontics, there is a significant interest in the problem of antibiotic therapy of aggressive forms of periodontitis; various modes of antibiotics are studied. Most studies of this pathology are devoted to the use of moxifloxacin, azithromycin and a combination of amoxicillin and metronidazole. Additional use of antibiotics leads to better results in the treatment of aggressive forms of periodontitis.
Subject. Modern medical care is not complete without the use of modern digital technologies — from remote patient registration and appointment, to remote diagnostics and laboratory tests, monitoring the condition of the patient. In most foreign countries and Russian medical institutions, telemedicine and digital technologies are actively used in the provision of dental care. The impact of digitalization of medical organizations as part of the transformation of the technological environment on the effectiveness of the organization of dental care services and patient satisfaction. The goal is to study the parameters of psychological resources of subjects of the treatment process that affect the development of digitalization. Develop an initiative to increase the benefits of digitalization in dental care. Methodology. Individual, tutored training in digitalization skills. Group forms of training (seminars, round tables, trainings). Results. Our research has shown that digitalization should start with the registry. This also implies improving the personal qualities and skills of both health professionals and patients. In addition, digitalization should also contribute to the development of comfort in the provision of dental services and improve the quality and safety of medical services provided. Conclusions. A resource-based approach in digital dentistry can be a conscious choice that can improve the efficiency of dental procedures and optimize workflows. In dental practice, saving time for performing auxiliary procedures means reducing the duration of appointments, increasing throughput, and increasing patient satisfaction in General and specific cases.
Thing. The significance of the study is associated with high prevalence of inflammatory diseases of paradontium and a variety of medications used for systemic treatment of the said pathology. Searching effective approaches aiming to achieve a required and adequate therapeutic effect excluding complications from unwanted effects and toxic side effects of systemic medications assumes the priority application of local delivery systems. Objective ― to study available literature data on local drug delivery systems as film forming transmucoid therapeutic systems in periodontology. Methodology. The study was based on searching and examination of scientific publications on film forming transmucoid therapeutic systems in databases of PubMed, eLIBRARY, Scopus, Web of Sciens, Medline. The materials were searched by the key words. Results. The review presents research data of different authors, explains the definition of transmucoid therapeutic systems, offers main classifications, describes methods of manufacture of polymer film systems and their characteristics, gives some variants of matrix membrane transport and the most popular representatives of the basement membrane. Conclusions. Studying literature helped to identify the diversity of the range, characteristics and advantages of applying transmucoid therapeutic systems used to treat inflammatory diseases of paradontium. Further detailed polymer researches focused to maintain chemical stability, specifics of diffusion, metabolism, solubility and dose-limiting toxicity are intended to increase safety and efficacy of applied local polymeric film delivery systems.
Object. The paper analyzes the change in the physical and chemical properties of mixed saliva in patients with the course of use of toothpaste "Sensodyne® Recovery and protection" containing NovaMin and sodium fluoride. The analysis of the survey of organoleptic properties of toothpaste, clinical examination of patients with hyperesthesia and laboratory parameters of mixed saliva in dynamics was carried out. Purpose. Rationale for the use of therapeutic and prophylactic toothpaste "Sensodyne® Recovery and protection" with sodium fluoride for sensitive teeth in young patients. Methodology. A clinical examination of the oral cavity of young patients (50 men, mean age of 22.50±2.59 years), index estimation of a condition of the teeth (CPUs, municipal production unitary enterprise), oral hygiene (J. R. Green, J. R. Vermillion, 1964), the determination of "teeth sensitivity" (method L. Y. Nut–Litovskogo S. B.); the study of mixed saliva (qualitative analysis, salumeria; concentration of fluorine ions and sodium, pH, redox potential, total zhestkost) exchange rate before and after application of toothpaste. Results. A pronounced clinical effect was obtained, which manifests itself in the cleansing qualities (p≤0.05), and in the elimination of hyperesthesia (p≤0.05) in all patients. The increase of pH values (p≤0.05) was revealed. After cleaning in the sample of mixed saliva, the concentration of fluoride ions increases by 22%, the content of sodium ions decreases by 35.4%, the content of calcium and magnesium ions decreases. This contributes to the formation of stable fluorapatite Ca5(PO4)3F in the surface layers of enamel. calcium ions from phosphosilicate calcium-sodium (NovaMin) go directly from the toothpaste "Sensodyne® repair and protect" with the sodium fluoride in the construction of the hydroxyapatite of tooth enamel. Summary. Thus, the analysis of the results of the survey evaluation of the organoleptic properties of toothpaste "Sensodyne® Recovery and protection" containing sodium fluoride, which are estimated to be highly valued, clinical examination of patients with hyperesthesia and laboratory parameters of mixed saliva in dynamics, showed a significant clinical effect: improving the cleaning ability of toothpaste, reducing the sensitivity of teeth in 100% of patients.
Thing. The experience of conducting professional oral hygiene in patients with chronic periodontitis in combination with drug-associated jaw osteonecrosis is presented. The goal is to identify the features of the oral cavity status of patients with chronic periodontitis and bisphosphonate osteonecrosis of the jaw (BONCH) on the background of postoperative chemotherapy after using two domestic mouthwashes (OML). Methodology. A clinical examination of the oral cavity of 15 patients aged 50 to 66 years was carried out, which were divided into two groups: the main group (after resection of the jaw segments) and the comparison group (5 and 10 people, respectively). Dental examination included examination of the oral cavity: the condition of periodontal tissues and mucous membrane, determination of the intensity of dental caries and hygiene and bleeding indices. Studies of mixed saliva (SS) were carried out before and after a single and daily course use of two domestic rinses based on chlorhexidine bigluconate and benzidamine and extracts of medicinal plants. Results. The pH value after the course application of OMLPR-1 in patients with BONCH has shifted from weakly acid (6.45 ± 0.4 units) to slightly alkaline (7.15 ± 0.15 units) medium. The structure of the SS before the application of OPLPR-1 was represented by small conglomerates of irregular shape and individual tree crystals of small sizes, and after the double use of OPLPR-1, the properties of the SS improved and medium-sized tree crystals appeared. After the course application of OPLR-2 in these patients, crystal-prismatic structures of a tree form were identified, a tendency to restore the structural properties of SS was determined. Findings. After the course application of LPRS, a tendency to restore the structural properties of SS was revealed. The course use of CPLR stimulates the excretion of SS, cleansing and a feeling of freshness in the mouth. The consecutive use of OPLR-1 and OPLR-2 helps to alleviate the condition of patients, especially against the background of BONCH and chemotherapy.
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