Basal cell carcinoma is the most frequent malignant tumor of the skin, and the most common carcinoma found in some countries. The main clinical subtypes of BCC are nodular, superficial, pigmented and morpheaform. The majority of the lesions appear on the head and neck, with a particular predilection on the upper central part of the face. Here we report a 62 year-old woman with two different morphological types of BCC which developed in the same area. The tumors have developed two months apart on the right paranasal region in close proximity. With the clinical examination and histopathological examination of punch biopsy specimens, the diagnoses of the lesions were confirmed as a nodular and an adenoid BCC. The tumors were totally removed with surgical excision. Neither recurrence nor new lesion was observed on the lesional or near areas in a 24-month follow-up period. To the best of our knowledge the presence of the two different morphological types of BCC in the same anatomical location has not been reported previously.
1.875 (p<0.001) and remained low at last follow-up for all patients with a median of 1.48 (p<0.001). Similarly, Skindex-29 scores at baseline were high at a median of 91, but declined to a median of 62 (p<0.01) at first post-radiotherapy visit, and declined to a median of 55 at last visit (p<0.001). Comparing responses across all time points for this patient population revealed a significant decrease in the mSWAT scores (pZ0.002) indicating good clinical objective response. There also was a significant improvement in the Skindex-29 scores with a considerable decline (p<0.001), demonstrating good subjective QOL response. Conclusion: This prospective study demonstrates excellent objective and subjective responses for mycosis fungoides treated with low dose (12 Gy in 12 fractions) TSET using the dual-field rotisserie technique with optional coverage of shadowed skin areas. The disease control rates and QOL should continue to be observed for ongoing feasibility as a treatment modality.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.