Background: Recurrent pregnancies loss (RPL) is physically andemotionally devasting situation for the parents, along with difficult situationfor obstetrician to handle.
Aim of the Work:The present study aimed at investigation of the significanceof various etiology in relation to pregnancy outcome in cases ofunexplained recurrent pregnancy loss. Materials And Methods: It is a retrospective analysis of 100 patientswho presented to El-Shatby maternity university hospital, betweenMay 2017 to October 2018, with history of two or more unexplained earlytrimester abortions fullfiling the common investigations done for thesecases. all the patients during mid-luteal phase, examined by transvaginal3D pulse Doppler ultrasound to detect endometrial perfusion with measuringin the sera 25-hydroxy vitamin D3 and B2 glycoprotein 1 antibodieswhich is a marker of antiphospholipid syndrome. evaluation of uterineartery blood flow and subendometrial blood flow, detection uterine arterypulsatility index (UAPI) and subendometrial blood flow presented by the indiciesvascularisation index (VI), flow index (FI) and vascular flow index(VFI).
Results and Conclusion:All of the studied parameters namely; doppler indices, vitamin D level and B2glycoprotien were significantly related to the incidence of the pregnancy loss and should be tested in those particular category of women who are at risk of recurrent pregnancy loss..
Background: Preterm labor represents one of the most likely causes for prenatal hospitalization. Previously, the accuracy of cervical length measurement in predicting preterm birth was thoroughly examined. The current study aimed to compare static and dynamic cervical assessment in prediction and management of preterm labor.Methods: The present study was prospective comparative study and conducted on (75) pregnant female patients recruited from the antenatal clinic of El-Shatby Maternity University hospital in the period from October 2021 till August 2022. The patients included in the study were divided into three groups; the first group included (25) patients and all were subjected to static cervical assessment, the second group included (25) patients and all were subjected to dynamic cervical assessment and the last group included (25) patients and all were subjected to interval dynamic cervical assessment. All groups are almost matched in their general characteristics. All groups received tocolysis in the form of nifedipine slow-release tablets 20 mg twice daily. Conventional static and dynamic transvaginal ultrasound assessment of cervical length (CL) was done.Results: There were inverse relationships between gestational age (GA), fundal level (FL) and mean gestational age (MGA) with the latency period but there was a direct relationship between the parity and the static cervical length in all the studied groups. There was a statistically significant difference between the studied groups regarding their means of latency period in those with static cervical length >1.5-2.5 cm (most of cases in all groups). Although there was statistically significant difference between group A, B and C as regard their means of static and dynamic cervical length.Conclusions: The longer the latency period, the lengthier the cervical length. The latency period had an inverse correlation with gestational age. There was also a direct relationship among parity and cervical length. The cervical estimation using the fundal pressure method, dynamic cervical length, is more enlightening than the interval approach.
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