5Multifunctional self-healing hydrogel coatings based on dynamic disulfide exchange reaction were developed via surface-initiated thiol-ene photopolymerization. The functional monomers, (poly(ethylene glycol)methyl ether methacrylate (PEGMA), N-hydroxyethyl acrylamide (HEAA) and 2-(methacryloyloxy)ethyl trimethylammonium chloride (META)), and disulfide-containing crosslinker bis(2-methacryloyl)oxyethyl disulfide (BMOD) were employed for the preparation of antifouling, 10 antibacterial and self-healing hydrogel coatings. The hydrogel coatings reduced protein adsorption, as well as bacteria adhesion from Gram-negative Escherichia coli (E. coli). Moreover, the coatings exhibited good self-healing ability at moderate temperatures due to the dynamic disulfide exchange reaction. Introduction of self-healing ability provides a promising means for self-repairing of microcracks of functional polymer coatings and improving their stability and durability in the long-term applications as 15 biomaterials.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.