Epigenetic dysregulation including DNA methylation and
histone
modifications is being increasingly recognized as a promising biomarker
for the diagnosis and prognosis of cancer. Herein, we devised a label-free
analytical toolbox comprising IR, UV–vis, CD spectroscopy,
and cyclic voltammetry, which is capable to differentiate significantly
hyper-methylated breast cancer chromosomes from the normal breast
epithelial counterparts.
Background: The common complications occurring during third stage of labor are PPH Retained Placenta, Morbid adherent placenta- placenta accreta, placenta increta, percreta, perineal tears, uterine inversion increasing the maternal morbidity and mortality. The objective of the present study was to evaluate percentage and spectrum of obstetrics complication occurring during third stage of labor.Methods: An observational study was done at Department of Obstetrics and Gynecology, People’s College of Medical Sciences and Research Center, Bhopal from January 2016 to December 2017. All women delivering vaginally including instrumental deliveries were included. The medio-lateral episiotomy was given to all primigravida and for multigravida decision was case based as big size babies, instrumental deliveries, rigid perineum. Active management of third stage of labor was practiced.Results: 899 women delivered vaginally during the study period of 2 years (Jan -Dec 2016 Jan -Dec 2017). Among these 6.45% (58 women) had various complications during third stage of labor . 55% were primigravida. Complications which were observed to occur during third stage of labor were perineal tear 4% (37/899 deliveries). Atonic PPH occurred in 0.5% (9/899 deliveries) Traumatic PPH was in 1.44% (13/899 deliveries and 0.3% cases had retained placenta. Associated condition in perineal tear cases were 92% had big size babies 5% cases were preterm labor and in 3% cases ventouse application was done.Conclusions: Common complications were 1st and 2nd degree perineal tears occurred in 4% deliveries and traumatic PPH were in 1.44% of cases.
We aim to review the causes, symptoms, and treatment for obese children. And what does an obese children problems the effect and problem? We can say complicated condition in which our body weight is more than desired weight according to height, weight, and age. Obesity is characterized differently for children and teenagers than it is for adults. Male child and Female children develop at various rates, and children are still growing. This condition leads to a a higher risk of getting other dangerous diseases like DM, HTN, etc. Childhood is the right time to pay attention; otherwise it will lead to obese adolescents and adults. Facts from different articles was amalgamated and shown in a simplified fashion, with the year of publication, the age of the children, sample size, study design, and study conclusions all taken into account. The key finding of this review was obesity is a major topic of concern today, especially in childhood. The lifestyle we have adapted in the present generation is more luxurious and physically less active. Obesity is the primary cause of a lot of diseases like diabetes mellitus, hypertension, thyroidism, even in younger children
This review article thoroughly covers a lot of ground, with references provided. It is a collection of various case studies that have been completed. As a result, this essay will only include essential information if anyone reads it. Childhood Obesity is a word used to describe a youngster who is considerably overweight for their age and height. Childhood obesity can lead to diabetes, high blood pressure, and high cholesterol.
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