Background: Gallbladder cancer is the most common malignant tumor of the biliary tract. The majority of cases are adenocarcinoma (AC). Pure squamous cell carcinoma (SCC) of gallbladder accounts only 3% of the malignant neoplasm of this organ. Methods: The medical records of all the patients who underwent cholecystectomy and specimen sent to the Pathology Department of Sardar Patel Medical College, Bikaner, in last five years were retrospectively analysed. Results: Out of total 1375 patients, 40 patients had gall bladder tumors and 1 (2.5%) patient had histological evidence of squamous cell carcinoma of gall bladder. The patient was 43 year old female. cholecystectomy was performed. Conclusion: Squamous cell carcinoma (SCC) is rare tumour of gall bladder. Keywords: Squamous cell carcinoma, Adenocarcinoma, Gall Bladder
Objectives: The objective of this study was to evaluate the histopathology and establish the correlation between placental changes in hypertensive disorders of pregnancy and fetal outcome. Methods: A cross-sectional study included 100 pregnant women with singletons admitted to the labor room with gestational ages >30 weeks and 35 weeks with hypertensive disorders of pregnancy between December 2021 and November 2022, admitted to the Department of Obstetrics and Gynecology, Sardar Patel Medical College, Bikaner. Shape of placenta, weight in grams, size, diameter in centimeters, and deposition were examined. Fetomaternal outcome was also noted. Results: Eighty percent (80) were in the age group of 21–30 years, with a mean age of 25.01±4.56 (range: 18–44 years). Only 35% of females were booked, and 63% of cases belonged to G1. Maximum cases were of pregnancy-induced hypertension (42%), followed by eclampsia (36%) and pre-eclampsia (16%), and the minimum case belonged to HELLP (1%). Although cases of placental infarction were higher in neonatal intensive care unit (NICU) admitted cases as compared to non-admitted cases (61.19% vs. 45.45%, respectively), calcification was higher in NICU-admitting cases as compared to non-admitting cases (95.52% vs. 84 vs. 5%, respectively). Syncytial knots were 94.03% vs. 81.82%, respectively, and grade fibrosis was 44.78% vs. 27.27%. Fibrinoid necrosis (71.64% vs. 54.55%) and leukocytic infiltration (68.66% vs. 63.64%). Statistically, no significant difference was observed in all parameters. Conclusion: Placental morphology and histopathology are affected in hypertensive pregnancies, which might be the reason for placental insufficiency in these cases.
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