In the early stages of cilia formation in the mouse airway epithelium, Chibby is recruited to the distal appendages of centrioles and is necessary for efficient ciliary vesicle formation and basal body docking at the apical cell membrane.
Heparan sulfate (HS) regulates the number and asymmetric division of germline stem cells (GSCs) in Drosophila testes. Hub-specific HS controls both stem cell number and functioning of the centrosome-anchoring machinery. The results suggest that HS-mediated niche signaling acts upstream of GSC division orientation control.
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