In many animal groups, factors required for germline formation are localized in germ plasm, a region of the egg cytoplasm. In Drosophila embryos, germ plasm is located in the posterior pole region and is inherited in pole cells, the germline progenitors. Transplantation experiments have demonstrated that germ plasm contains factors that can form germline, and germ plasm also directs abdomen formation. Genetic analysis has shown that a common mechanism directs the localization of the abdomen and germline-forming factors to the posterior pole. The critical factor for abdomen formation is the nanos (nos) protein (nanos). Here we show that nos is also essential for germline formation in Drosophila; pole cells lacking nanos activity fail to migrate into the gonads, and so do not become functional germ cells. In such pole cells, gene expression, which normally initiates within the gonad, begins prematurely during pole-cell migration. Premature activation of genes in germline precursors may mean that these cells fail to develop normally. A function for nos protein in Drosophila germline formation is compatible with observations of its association with germ plasm in other animals.

Continuous, coherent subterahertz radiation arises when a dc voltage is applied across a stack of the many intrinsic Josephson junctions in a Bi2Sr2CaCu2O(8+δ) single crystal. The active junctions produce an equal number of I-V characteristic branches. Each branch radiates at a slightly tunable frequency obeying the Josephson relation. The overall output is broadly tunable and nearly independent of heating effects and internal cavity frequencies. Amplification by a surrounding external cavity to allow for the development of a useful high-power source is proposed.

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Strong, monochromatic, coherent and continuous terahertz (THz) radiation was generated from the intrinsic Josephson junctions in a cylindrical stand-alone mesa sandwich structure fabricated from a single crystal of the high-temperature superconductor Bi2Sr2CaCu2O8+δ. By varying the base temperature and the dc bias current-voltage characteristic (IVC) points, the emission frequency is tunable from 0.5 to a record high 2.4 THz observed on two inner IVC branch points. Strong emission power peaks were observed at 1.0 THz and 1.6 THz. This device is hence an excellent candidate to fill the “THz gap” between ∼1.4 and 2.0 THz.

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To obtain higher power P and frequency f emissions from the intrinsic Josephson junctions in a high-Tc superconducting Bi2Sr2CaCu2O8+δ single crystal, we embedded a rectangular stand-alone mesa of that material in a sandwich structure to allow for efficient heat exhaust. By varying the current-voltage (I-V) bias conditions and the bath temperature Tb, f is tunable from 0.3 to 1.6 THz. The maximum P of a few tens of μW, an order of magnitude greater than from previous devices, was found at Tb∼55 K on an inner I-V branch at the TM(1,0) cavity resonance mode frequency. The highest f of 1.6 THz was found at Tb=10 K on an inner I–V branch, but away from cavity resonance frequencies. A possible explanation is presented.

High-power, continuous, broadly tunable THz radiation from 0.29 to 1.06 THz, was obtained from the outer current-voltage characteristic (IVC) branch of a single stand-alone mesa of the high-transition temperature Tc superconductor Bi2Sr2CaCu2O8+δ. The particular metallic film structures placed both beneath and atop the mesas resulted in more efficient heat dissipation, higher allowed applied dc voltages, larger IVC loops, wider emission temperature ranges, and much broader emission frequency tunability than obtained previously.

Coherent and continuous radiation sources of the electromagnetic (EM) waves at terahertz (1 THz = 10 12 c/s) frequencies using a mesa structure fabricated from high temperature superconducting Bi 2 Sr 2 CaCu 2 O 8þ single crystals are described with a special emphasis on the physics of the radiation mechanism and the applications. After the intensive studies of many mesas fabricated with different conditions, it is revealed that the ac-Josephson effect works as a primary driving mechanism of the radiation and the cavity resonance needed for stronger radiation plays an additional role to the mechanism, although both are working together while radiating. A prototype of the imaging machine for multipurpose uses has successfully been developed. #