Localized surface plasmon resonance (LSPR) attracts attention for the fabrication of a biosensor because it can be used easily and is highly sensitive to the change in surface reflective index. Anodic aluminum oxide (AAO) has self-assembled nanoholes and is fabricated easily all over the Al substrate. The depth and diameter of the nanoholes are easily controlled by changing the etching solution and applied voltage. By depositing a Au thin film on the AAO substrate, the sensitivity of the sensor chip was affected by both optical interference and LSPR. In this study, the optical property of the AAO-based LSPR sensor chip was characterized on the basis of the nanostructure. We presented a biosensing application of the AAO-based LSPR sensor chip. The highest sensitivity of the sensor chip was observed at the AAO nanohole diameter of 75 nm and the AAO nanohole depth of 0.5 µm, when bovine serum albumin (BSA) adsorbed on the sensor chip.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.