apillary fibroelastomas, which are generally found on the valvular endocardium, are relatively uncommon benign tumors and the next most common of the primary cardiac tumors after myxomas and lipomas. 1,2 However, they can cause lethal embolisms resulting in myocardial infarction, cerebral infarction and pulmonary embolism. 2 The number of patients diagnosed with papillary fibroelastomas has increased since the advent of echocardiography, but cases of recurrence have not been reported and multiple occurrence is rare. [3][4][5][6][7][8][9][10][11] We present a case of double papillary fibroelastoma of the aortic valve with aortic regurgitation and mitral periprosthetic leakage occurring 4 years after resection of an initial left ventricular papillary fibroelastoma with mitral and tricuspid valvular disease.
Case ReportIn 1997, a 52-year-old man presented to hospital with dyspnea and a medical history that included atrial fibrillation in 1993. Cardiac catheterization revealed mild pulmonary hypertension of 45/22 mmHg, elevated wedge pressure of 22 mmHg, and obstruction of the posterior descending artery. Transthoracic echocardiography confirmed the presence of a left ventricular tumor (Fig 1A), and revealed moderate mitral stenosis and regurgitation, tricuspid regurgitation and trivial aortic regurgitation. Mitral valve replacement (29 mm Carbomedics Valve), tricuspid annuloplasty (32 mm Carpentier Ring) and tumor excision without blood transfusion were performed. The tumor, found on the anterior wall of the left ventricle near the apex of the heart, was pale yellow and 7 mm in maximum length. It was excised through the mitral valve (Fig 2A). Pathology showed papillary growth with myxoid stroma and the
To avoid the problem of valve prosthesis/patient mismatch in the late postoperative period, we have adopted patch enlargement of the small aortic annulus in 33 patients having undergone aortic valve replacement since 1975, when the aortic annulus could not accept a large enough prosthesis. The mean age was 40 years, including 2 children aged 4. The technique of patch enlargement utilized was Nicks' method wherein the incision does not extend onto the mitral leaflet. In 31 adult patients, the aortic annulus before enlargement ranged in diameter from 18 to 24 mm with an average of 20.8 mm. After enlargement, the diameter of the annulus was 25.0 mm on average. In 2 children, the mean diameter of the annulus was enlarged from 16.5 mm to 20.5 mm. There were 2 early deaths in the initial series and 2 late deaths. Patch enlargement of the small aortic annulus is a simple, safe, and effective adjunct permitting the insertion of a valve one or two sizes larger than that which could be accommodated by the native annulus.
Two patients each with a rare combination of aortic coarctation and annuloaortic ectasia underwent successful single-stage repair in which the aortic root was reconstructed with a valved conduit, and an extra-anatomical bypass was made by grafting from the ascending to the abdominal aorta. Although the long-term outcome of such a long extra-anatomical bypass graft has not yet been established, the use of the graft for reducing the risk to coarctation-related complications during the early and late postoperative periods appears promising.
The objective of this study was to investigate the difference between the closed circuit system and the open circuit system in clinical heparin-coated cardiopulmonary bypass (CPB) circuits with a centrifugal pump. We evaluated the coagulation, fibrinolysis, and inflammatory response in valvular heart surgery. Nineteen patients were assigned at random to a group for the closed circuit system or the open circuit system. This is the first report on the effect of a closed circuit in valvular surgery. We measured the platelet count, white blood cell count, plasma fibrinogen concentration, thrombin-antithrombin III complex, plasmin-Alpha2 plasmin inhibitor complex, D-dimer, interleukin-6, polymorphic neutrophil-elastase, and the plasma free hemoglobin. Blood samples were collected before the start of perfusion, 15 and 60 min after the start of perfusion, 60 min after the administration of protamine, and 1 day after the operation. During the perfusion, coagulation, fibrinolysis, and inflammatory responses were activated; however, no significant differences between the two groups were noted. In this clinical investigation with suction and the cell saving system, the closed circuit was not found to be superior to the open circuit with regard to biocompatibility.
We performed modified aortic root replacement using a composite graft in seven patients over a 7-year-period. Six patients underwent emergency surgery for acute aortic dissection and one patient underwent elective surgery for an aortic aneurysm. To make the composite graft, we chose an artificial valve that was 1 mm larger than the graft, and when performing the proximal anastomosis, we sutured only the graft edge using the horizontal mattress suture technique, applying an additional running suture for reinforcement. The button technique was routinely used for coronary reattachment. To assess hemostasis of the aortic proximal and coronary suture line, cardioplegia was injected via the left atrial vent, which enabled us to confirm hemostasis before performing the distal anastomosis. Blood loss and the need for blood transfusion were minimized by this modified technique. None of the six survivors has required reoperation during 7-year period. Our technique of aortic root replacement based on a composite graft with some operative modifications seems to be safe and reliable, resulting in a satisfactory outcome.
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