Objective: Post-operative acute kidney injury (AKI) is a frequent surgical complication. Data on this disorder are scare in our setting. We aimed to study the prevalence, characteristics and outcome of postoperative AKI in Cameroon. Methods: A prospective and analytical study from December 2020 to Mai 2021 including all consenting adults’ patients admitted in the departments of surgery, obstetrics/gynecology and intensive care unit (ICU) of 3 referral hospitals in Douala. For each patient, 3 serum creatinine assays were done on admission before the surgery, on days 2 and 7 after surgery. Postoperative AKI was defined and classified according to the modified KDIGO 2012 criteria. Outcome measure were kidney recovery at day 7 and mortality. Kidney recovery was total if serum creatinine on day 7 was less or equal to the preoperative value, partial if less than diagnostic value of day 2 but not the preoperative value and absent if creatinine on day 7 did not decrease or if the patient required dialysis. p <0.05 was considered significant. Result: Out of 203 patients included, 52 developed postoperative AKI, giving a prevalence of 26.6%. Mean age of AKI patients was 35.34 (13.74) years with 61.6% being (32/52) male; AKI stage 1 accounts for 55.7% (29/52), 19.3% (10/52) stage 2 and 25% (13/52) stage 3. AKI was functional in 61.5% (32/52) of cases mainly due to hypovolemia 42.5% (22/52) and sepsis 34.6% (18/52). For the 40 patients diagnosed on D2, kidney recovery was known in 75% (30/40); with 66.6% (20/30) total recovery, 23.4% (7/30) partial recovery and 10 % (3/30) without recovery. Mortality rate was 19% (10/52) mainly due to hemorrhagic shock. Intra operative hypotension (aOR: 6.09; CI: 1.4 - 26.33; p = 0.016) and dirty surgery (aOR: 6.22; CI: 1.35 - 28.75; p = 0.019) were factors associated with AKI. Conclusion: Postoperative AKI occurred in 1/4 of patients in our setting. It is mainly due to hypovolemia and sepsis, renal recovery and mortality were high.
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.
hi@scite.ai
10624 S. Eastern Ave., Ste. A-614
Henderson, NV 89052, USA
Copyright © 2024 scite LLC. All rights reserved.
Made with 💙 for researchers
Part of the Research Solutions Family.