There are a lot of optical sensors for the selective determination of ion species1. Some organic compounds also have been determined by optical sensors using the enzymatic and immunological reactions. On the other hand, calixarenes are well known as novel host molecules, and specific guest ions or molecules can be incorporated inside the cavity of calixarenes. This specific recognition function of calixarene has been applied to the development of electrochemical and optical ion sensors. However, an optical sensing of organic molecules using this host-guest system is a new approach at present7. In this study, a sensing membrane containing a fluorescent probe and a caiixarene derivative is prepared, and it is attached on a distal end of an optical fiber. An organic compound, which specially interacts with the calixarene derivative, is optically determined. The response mechanism of the sensor is discussed.
Intracranial perfusion failure is one of the well-documented complications of bilateral radical neck dissection, but rarely occurs after unilateral radical neck dissection. We describe a male patient who had intracranial perfusion failure after unilateral radical dissection of the right side of the neck. Three days after the dissection, he complained of severe headache and nausea and then had increased blood and intracranial pressures. Carotid angiograms showed dominant right transverse sinus drainage probably because of hypoplastic left transverse sinus drainage. Furthermore, dissection of the right internal jugular vein caused occlusion at the superior bulb of the right jugular vein, leading to intracranial perfusion failure. The patient was treated by drainage of cerebrospinal fluid and a dehydrator and became asymptomatic. In our patient radical neck dissection done on the side of the dominant transverse sinus drainage, caused intracranial perfusion failure followed by severe headache and nausea, possibly because of the hypoplastic contralateral transverse sinus drainage.
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