The purpose of this study was to report a patient with acute zonal occult outer retinopathy (AZOOR) unilaterally, who received steroid pulse therapy. A 42-year-old woman presented with photopsias and severe vision loss in her left eye. Visual acuity was 0.04, and Humphrey visual field testing showed overall depression with a mean deviation (MD) value of -25.78 dB in the left eye. Fundus and angiographic examinations found no specific abnormal findings, leading to a diagnosis of AZOOR. Optical coherence tomography showed attenuation of the photoreceptor inner segment/outer segment junction (IS/OS) line. Focal macular electroretinography (fmERG) demonstrated that there were non-detectable responses at 5°, 10° and 15° (in diameter). Following steroid pulse therapy, her visual acuity was 1.0, her MD value improved to -16.08 dB, and there were both partial recovery of the IS/OS line and apparent improvements of fmERG responses (at 10° and 15°). The present findings suggest that steroid pulse therapy might potentially be an effective treatment in some AZOOR patients.
We evaluated cyanopsia by means of achromatic-point settings at several time points started from the day before intraocular lens (IOL) implantation for cataract removal surgery. We intensively measured the initial drift in color appearance; we started the measurement less than 30 min after eyepatch removal, and the measurement continued for several weeks. The shifts were mainly observed in the direction of color space that selectively varies short-wavelength-sensitive cone (S-cone) responses. The time constant of shifts in color appearance was estimated at the initial stage of cyanopsia by fitting exponential curves. The result of fitting suggests that color appearance is recalibrated during cyanopsia by some neural mechanisms with a time constant of several hours. It also became clear that the migration of the achromatic point becomes slower within approximately 12 h after eyepatch removal.
We evaluated the usefulness of the Waggoner Hardy-Rand-Rittler pseudoisochromatic plate (W-HRR) in subjects with anomalous trichromacy of congenital red-green color blindness. Materials and Methods: Sixteen protanomals and 38 deuteranomals who were diagnosed with a Nagel Type I anomaloscope were examined using the Richmond HRR pseudoisochromatic plate (R-HRR) and the W-HRR. The results of the W-HRR were then compared with the results of the R-HRR
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