SUMMARYA comparative study has been made of the blood rheology, and its component factors, in horse, sheep, cattle, goat, camel, pig, dog, rabbit and man. The erythrocyte flexibility of horse red cells is high relative to man, that of pig, dog, camel and rabbit comparable, but less flexible, and sheep, cattle and goat relatively inflexible. The erythrocyte flexibility of horse, sheep, cattle and goats does not vary with the plasma fibrinogen level, as occurs with human and rabbit cells. Washing erythrocytes and then suspending them in isotonic saline makes the erythrocytes of all species relatively inflexible. There is a factor in horse plasma, which is not fibrinogen, that makes horse and human erythrocytes suspended in it very flexible. The blood viscosity of all species is comparable at high shear rates (230 s-') due to the shape of the cells compensating for their flexibility. The variations of blood viscosity at low shear rates (11-5 s-1) were also found to depend on the erythrocyte flexibility, and only influenced indirectly by the fibrinogen concentration. There is no significant effect of temperature on the erythrocyte flexibility of horse, sheep, cattle, goat and a small number of human subjects. This is reflected in the way the viscosity of these bloods varies with temperature.
The early postoperative period is a crucial stage in a patient's recovery as they are susceptible to a range of complications, with detection and management the key to avoiding long term consequences.Wearable devices are an innovative way of monitoring patient's post-intervention and may translate into improved patient outcomes, and reduced strain on healthcare resources, as they may facilitate safer and earlier discharge from the hospital setting. Several recent studies have investigated the use of wearable devices in postoperative monitoring. This review outlines the current literature including the range of wearable devices used for postoperative monitoring, the variety of surgeries investigated, and the outcomes assessed.A search of five electronic databases was performed. Data on the range of wearable devices, outcomes and surgeries investigated were extracted and synoptically analysed. Twenty-four articles were retrieved. Data on several different types of surgery were available and discussed. Most studies used wrist-mounted wearable devices and accelerometers or pedometers to assess physical activity metrics, including step counts and physical activity intensity (PAI), as markers of recovery. Wearable devices can provide objective data capture in the early postoperative phase to remotely monitor patients using various metrics including temperature, cardiac monitoring and physical activity. The majority of current research is focussed on wrist-mounted accelerometers and pedometers used to assess physical activity as a marker of postoperative function. Further research is required to demonstrate improved safety and cost-effectiveness of this technology.
The emergence of 3D-Printing technologies and subsequent medical applications have allowed for the development of Patient-specific implants (PSIs). There have been increasing reports of PSI application to spinal surgery over the last 5 years, including throughout the spine and to a range of pathologies, though largely for complex cases. Through a number of potential benefits, including improvements to the implant–bone interface and surgical workflow, PSIs aim to improve patient and surgical outcomes, as well as potentially provide new avenues for combating challenges routinely faced by spinal surgeons. However, obstacles to widespread acceptance and routine application include the lack of quality long-term data, research challenges and the practicalities of production and navigating the regulatory environment. While recognition of the significant potential of Spinal PSIs is evident in the literature, it is clear a number of key questions must be answered to inform future clinical and research practices. The spinal surgical community must selectively and ethically continue to offer PSIs to patients, simultaneously allowing for the necessary larger, comparative studies to be conducted, as well as continuing to provide optimal patient care, thereby ultimately determining the exact role of this technology and potentially improving outcomes.
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