Kounis syndrome represents the concurrence of acute coronary syndromes or anginal pain with allergic, hypersensitivity, and anaphylactic reactions. It can be associated with normal coronary angiogram or preexistent coronary pathology. Idiopathic anaphylaxis is defined as anaphylaxis without any identifiable precipitating agent or event. We present a case of male who experienced attacks of dyspnoea, hypoxemia, hypotension, purple-red skin, and chest pain over several years. He was diagnosed with idiopathic anaphylaxis. Based on the pattern of chest pain of ischemic origin during the attacks he was retrospectively diagnosed with Kounis syndrome.
Patient: Female, 44Final Diagnosis: Deterioration of renal and heart functionSymptoms: HypercalcemiaMedication: —Clinical Procedure: LaboratorySpecialty: NephrologyObjective:Rare diseaseBackground:Fabry disease is a rare and progressive X-linked inherited disorder of glycosphingolipid metabolism that is due to deficient or absent lysosomal α-galactosidase A activity. Among its other associated signs and symptoms, patients present with renal failure and proteinuria, which are markers of disease progression. Renin-angiotensin-aldosterone system (RAAS) blockers can slow the progression of chronic renal failure and proteinuria. In fact, some studies have shown the beneficial effects of paricalcitol on proteinuria.Case Report:We present a case of a female patient with the classic variant of Fabry disease. She was treated with a high dose of paricalcitol as an antiproteinuric agent due to unsatisfactory double-RAAS blockage, which resulted in transient worsening of cardiac and renal function.Conclusions:Despite the positive effects of paricalcitol as an antiproteinuric agent, as previously shown by some authors, our case highlights the possible serious adverse effects associated with the use of high doses of this drug.
IzvlečekŽelve so pogosti hišni ljubljenčki in znan rezervoar okužb s salmonelami. V literaturi se opisuje predvsem prenos okužb z uživanjem slabo toplotno obdelanega želvjega mesa, obstajajo pa tudi posamezni opisi prenosa okužbe z želve kot hišnega ljubljenčka in vode, v kateri so bivale želve. V našem prispevku predstavljamo primera dveh bolnic, hospitaliziranih zaradi akutnega gastroenterokolitisa ob okužbi s Salmonella-o Chester, preneseno iz vode, v kateri sta bivali želvi rumenovratki, in epidemiološko poročilo o dogodkih, povezanih z okužbo. AbstractTurtles are common as pets and represent a known reservoir for salmonellosis. There are few epidemic outbreaks of salmonellosis linked to ingestion of undercooked turtle meat described in the literature. A few cases of pet turtle borne infection and infection due to aquarium water contamination have been described. We present cases of two female patients hospitalized due to acute gastroenterocolitis caused by Salmonella Chester and the epidemiological report of events related to the infection outbreak. The infection was transmitted from the water of a private aquarium with two pet turtles.
Our results on in-hospital glycemia management seem comparable to previously published data. Patients with newly discovered diabetes, type 1 diabetes, treated with steroids and those eating improperly should be closely monitored. Additional education on guidelines and steroid-induced hyperglycemia accompanied by updated medical charts represent possible improvements. Quality standards for in-hospital glycemia management should be established.
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